Complement system

Kim B. Yancey, Zelmira Lazarova

Research output: Chapter in Book/Report/Conference proceedingChapter


Complement plays an important role in inflammation, opsonization of foreign materials, facilitation of phagocytosis by leukocytes, and direct cytotoxic reactions. The complement system is divided into three segments: initiation mechanisms, the amplification pathway, and the membrane attack complex. The initiation mechanisms are the classic, alternative, and lectin pathways. The complement system displays continuous, low-grade activation.

Original languageEnglish (US)
Title of host publicationClinical and Basic Immunodermatology
PublisherSpringer London
Number of pages14
ISBN (Print)9781848001640
StatePublished - Dec 1 2008

ASJC Scopus subject areas

  • Medicine(all)


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