TY - JOUR
T1 - Combined use of intravascular lithotripsy and brachytherapy
T2 - A new approach for the treatment of recurrent coronary in-stent restenosis
AU - Nikolakopoulos, Ilias
AU - Vemmou, Evangelia
AU - Xenogiannis, Iosif
AU - Brilakis, Emmanouil S.
N1 - Funding Information:
Dr. Nikolakopoulos: nothing to disclose; Dr. Vemmou nothing to disclose; Dr. Xenogiannis: nothing to disclose; Dr. Brilakis: consulting/speaker honoraria from Abbott Vascular, American Heart Association (associate editor Circulation), Amgen, Biotronik, Boston Scientific, Cardiovascular Innovations Foundation (Board of Directors), ControlRad, CSI, Ebix, Elsevier, GE Healthcare, InfraRedx, Medtronic, Siemens, and Teleflex; research support from Regeneron and Siemens. Shareholder: MHI Ventures.
Publisher Copyright:
© 2020 Wiley Periodicals LLC.
PY - 2021/6/1
Y1 - 2021/6/1
N2 - Treatment of coronary in-stent restenosis (ISR) is challenging and often requires combination of multiple treatment modalities. Coronary intravascular lithotripsy (IVL) has been successfully used for treating stent under-expansion, but is not currently commercially available in the United States. We present three recurrent coronary ISR cases in which multiple treatment modalities (high-pressure balloon inflation, plaque modification balloons, and laser with contrast injection) failed. These patients were treated with a combination of IVL (peripheral IVL catheter used off-label in the coronary arteries) and brachytherapy. Due to the high IVL balloon profile, delivery via femoral or radial access was challenging, requiring 7–8 French guide catheters. IVL was performed delivering 4–8 treatments of 20 pulses each with a favorable final angiographic and intravascular ultrasound result. All patients were angina free 1 month after the procedure.
AB - Treatment of coronary in-stent restenosis (ISR) is challenging and often requires combination of multiple treatment modalities. Coronary intravascular lithotripsy (IVL) has been successfully used for treating stent under-expansion, but is not currently commercially available in the United States. We present three recurrent coronary ISR cases in which multiple treatment modalities (high-pressure balloon inflation, plaque modification balloons, and laser with contrast injection) failed. These patients were treated with a combination of IVL (peripheral IVL catheter used off-label in the coronary arteries) and brachytherapy. Due to the high IVL balloon profile, delivery via femoral or radial access was challenging, requiring 7–8 French guide catheters. IVL was performed delivering 4–8 treatments of 20 pulses each with a favorable final angiographic and intravascular ultrasound result. All patients were angina free 1 month after the procedure.
KW - coronary restenosis
KW - lithotripsy
KW - percutaneous coronary intervention
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U2 - 10.1002/ccd.29332
DO - 10.1002/ccd.29332
M3 - Article
C2 - 33031640
AN - SCOPUS:85092181433
SN - 1522-1946
VL - 97
SP - 1402
EP - 1406
JO - Catheterization and Cardiovascular Interventions
JF - Catheterization and Cardiovascular Interventions
IS - 7
ER -