Colonization of gnotobiotic piglets by a luxS mutant strain of Escherichia coli O157:H7

Dianna M. Jordan, Vanessa Sperandio, James B. Kaper, Evelyn A. Dean-Nystrom, Harley W. Moon

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Gnotobiotic piglets inoculated with Escherichia coli O157:H7, its luxS mutant derivative, or nonpathogenic E. coli were evaluated for attaching and effacing lesions. Although no differences in clinical symptoms were seen between pigs inoculated with the parent and those inoculated with the luxS mutant, the luxS mutant-inoculated pigs had a lower frequency of attaching and effacing lesions in the spiral colon than parent strain-inoculated pigs.

Original languageEnglish (US)
Pages (from-to)1214-1216
Number of pages3
JournalInfection and immunity
Volume73
Issue number2
DOIs
StatePublished - Feb 2005

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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