Clinical application of GAFCHROMIC® EBT film for in vivo dose measurements of total body irradiation radiotherapy

Fan Chi Su; Chengyu Shi; Niko Papanikolaou

doi:10.1016/j.apradiso.2007.09.015

Clinical application of GAFCHROMIC^® EBT film for in vivo dose measurements of total body irradiation radiotherapy

Fan Chi Su, Chengyu Shi, Niko Papanikolaou

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

The GAFCHROMIC^® EBT film model is a fairly new film product designed for absorbed dose measurements of high-energy photon beams. In vivo dosimetry for total body irradiation (TBI) remains a challenging task due to the extended source-to-surface distance (SSD), low dose rates, and the use of beam spoilers. EBT film samples were used for dose measurements on an anthropomorphic phantom using a TBI setup. Additionally, in vivo measurements were obtained for two TBI patients. Phantom results verified the suitability of the EBT film for TBI treatment in terms of accuracy, reproducibility, and dose linearity. Doses measured were compared to conventional dosimeter measurements using thermoluminescent dosimeters (TLDs), resulting in an agreement of 4.1% and 6.7% for the phantom and patient measurements, respectively. Results obtained from the phantom and patients confirm that GAFCHROMIC^® EBT films are a suitable alternative to TLDs as an in vivo dosimeter in TBI radiotherapy.

Original language	English (US)
Pages (from-to)	389-394
Number of pages	6
Journal	Applied Radiation and Isotopes
Volume	66
Issue number	3
DOIs	https://doi.org/10.1016/j.apradiso.2007.09.015
State	Published - Mar 2008
Externally published	Yes

Keywords

GAFCHROMIC EBT
In vivo dosimetry
Radiation dosimetry
Radiochromic film
Total body irradiation

ASJC Scopus subject areas

Radiation

Access to Document

10.1016/j.apradiso.2007.09.015

Cite this

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title = "Clinical application of GAFCHROMIC{\textregistered} EBT film for in vivo dose measurements of total body irradiation radiotherapy",

abstract = "The GAFCHROMIC{\textregistered} EBT film model is a fairly new film product designed for absorbed dose measurements of high-energy photon beams. In vivo dosimetry for total body irradiation (TBI) remains a challenging task due to the extended source-to-surface distance (SSD), low dose rates, and the use of beam spoilers. EBT film samples were used for dose measurements on an anthropomorphic phantom using a TBI setup. Additionally, in vivo measurements were obtained for two TBI patients. Phantom results verified the suitability of the EBT film for TBI treatment in terms of accuracy, reproducibility, and dose linearity. Doses measured were compared to conventional dosimeter measurements using thermoluminescent dosimeters (TLDs), resulting in an agreement of 4.1% and 6.7% for the phantom and patient measurements, respectively. Results obtained from the phantom and patients confirm that GAFCHROMIC{\textregistered} EBT films are a suitable alternative to TLDs as an in vivo dosimeter in TBI radiotherapy.",

keywords = "GAFCHROMIC EBT, In vivo dosimetry, Radiation dosimetry, Radiochromic film, Total body irradiation",

author = "Su, {Fan Chi} and Chengyu Shi and Niko Papanikolaou",

year = "2008",

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doi = "10.1016/j.apradiso.2007.09.015",

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AU - Shi, Chengyu

AU - Papanikolaou, Niko

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N2 - The GAFCHROMIC® EBT film model is a fairly new film product designed for absorbed dose measurements of high-energy photon beams. In vivo dosimetry for total body irradiation (TBI) remains a challenging task due to the extended source-to-surface distance (SSD), low dose rates, and the use of beam spoilers. EBT film samples were used for dose measurements on an anthropomorphic phantom using a TBI setup. Additionally, in vivo measurements were obtained for two TBI patients. Phantom results verified the suitability of the EBT film for TBI treatment in terms of accuracy, reproducibility, and dose linearity. Doses measured were compared to conventional dosimeter measurements using thermoluminescent dosimeters (TLDs), resulting in an agreement of 4.1% and 6.7% for the phantom and patient measurements, respectively. Results obtained from the phantom and patients confirm that GAFCHROMIC® EBT films are a suitable alternative to TLDs as an in vivo dosimeter in TBI radiotherapy.

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