Circadian Rhythm Regulation by Pacemaker Neuron Chloride Oscillation in Flies

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Abstract

Circadian rhythms in physiology and behavior sync organisms to external environmental cycles. Here, circadian oscillation in intracellular chloride in central pacemaker neurons of the fly, Drosophila melanogaster, is reviewed. Intracellular chloride links SLC12 cation-coupled chloride transporter function with kinase signaling and the regulation of inwardly rectifying potassium channels.

Original languageEnglish (US)
Pages (from-to)0
Number of pages1
JournalPhysiology
Volume39
Issue number3
DOIs
StatePublished - May 1 2024

Keywords

  • SLC12
  • SPAK
  • WNK
  • circadian
  • potassium channel

ASJC Scopus subject areas

  • Physiology

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