TY - JOUR
T1 - Chronic kidney disease in children
T2 - Recent update
AU - Pirojsakul, Kwanchai
AU - Mathews, Nisha
AU - Seikaly, Mouin G.
N1 - Publisher Copyright:
© Pirojsakul et al.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2015
Y1 - 2015
N2 - The incidence of end stage of renal disease (ESRD) in US children age 0-19 years is 12.9 per million/year (2012). The economic and social burden of diagnosing, treating and preventing chronic kidney disease (CKD) in children and adults remains substantial. Advances in identifying factors that predict development of CKD and its progression, as well as advances in the management of co-morbid conditions including anemia, cardiovascular disease, growth, mineral and bone disorder, and neurocognitive function are discussed. Despite recent reports from retrospective registry data analysis and multi-center prospective studies which have significantly advanced our knowledge of CKD, and despite advances in the understanding of the pathogenesis, diagnosis and treatment of CKD much work remains to be done to improve the long term outcome of this disease.
AB - The incidence of end stage of renal disease (ESRD) in US children age 0-19 years is 12.9 per million/year (2012). The economic and social burden of diagnosing, treating and preventing chronic kidney disease (CKD) in children and adults remains substantial. Advances in identifying factors that predict development of CKD and its progression, as well as advances in the management of co-morbid conditions including anemia, cardiovascular disease, growth, mineral and bone disorder, and neurocognitive function are discussed. Despite recent reports from retrospective registry data analysis and multi-center prospective studies which have significantly advanced our knowledge of CKD, and despite advances in the understanding of the pathogenesis, diagnosis and treatment of CKD much work remains to be done to improve the long term outcome of this disease.
KW - Anemia
KW - Bone disorder
KW - Cardiovascular disease
KW - Chronic kidney disease
KW - Growt
KW - Hypertension
KW - Neurocognitive deficit
KW - Proteinuria
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U2 - 10.2174/1874303x015080100117
DO - 10.2174/1874303x015080100117
M3 - Article
AN - SCOPUS:84953737515
SN - 1874-303X
VL - 8
SP - 117
EP - 123
JO - Open Urology and Nephrology Journal
JF - Open Urology and Nephrology Journal
IS - Suppl 3: M5
ER -