Chromatin remodeling and Rb activity

J. William Harbour, Douglas C. Dean

Research output: Contribution to journalReview articlepeer-review

115 Scopus citations


Progression of cells through the cell cycle is central to normal cell proliferation, and checkpoints that regulate this cycle are targets of tumorigenic mutations. One of these checkpoints is the Rb family of proteins that seems to regulate exit of cells from both G1 and S phase of the cell cycle. Recent studies have linked the function of the Rb family to chromatin remodeling enzymes.

Original languageEnglish (US)
Pages (from-to)685-689
Number of pages5
JournalCurrent Opinion in Cell Biology
Issue number6
StatePublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology


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