Chloral hydrate toxicity in a term infant

M. A. Anyebuno, C. R. Rosenfeld

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Chlorate hydrate is commonly used for neonatal sedation, but blood levels are infrequently monitored, reflecting an underemphasis of acute toxic effects. This report describes a case of chloral hydrate toxicity in a term infant with cardiac, renal, neurologic, bladder and gastrointestinal dysfunction. The effects of exchange transfusion are described as well as pharmacokinetics.

Original languageEnglish (US)
Pages (from-to)116-120
Number of pages5
JournalDevelopmental Pharmacology and Therapeutics
Issue number1-2
StatePublished - Jan 1 1991


  • Chloral hydrate
  • Ileus
  • Term infant
  • Trichloroethanol

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)


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