Chemically induced pluripotent stem cells (CiPSCs): A transgene-free approach

Shigeo Masuda, Jun Wu, Tomoaki Hishida, Ganesh N. Pandian, Hiroshi Sugiyama, Juan Carlos Izpisua Belmonte

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Induced pluripotent stem cells (iPSCs) could be generated by a single gene Oct4 and chemical compounds, in which exogenous expression of Oct4 was indispensable for reprogramming. Recent advances in chemical-mediated cellular reprogramming suggest that small molecules alone (i.e. without Yamanaka factors) can successfully establish iPSCs from mouse somatic cells.

Original languageEnglish (US)
Pages (from-to)354-355
Number of pages2
JournalJournal of molecular cell biology
Issue number5
StatePublished - Oct 2013
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cell Biology


Dive into the research topics of 'Chemically induced pluripotent stem cells (CiPSCs): A transgene-free approach'. Together they form a unique fingerprint.

Cite this