TY - JOUR
T1 - Changing role of hyaluronidase in plastic surgery
AU - Bailey, Steven H.
AU - Fagien, Steven
AU - Rohrich, Rod J.
PY - 2014/2
Y1 - 2014/2
N2 - Soft-tissue augmentation has become an increasingly popular option for facial rejuvenation. Hyaluronic acid fillers are part of the most rapidly expanding segment of this market, largely because of their safe drug profile and temporary nature. Despite their good safety profile, they can and do have complications ranging from superficial placement, uneven placement, granulomatous reactions, and skin necrosis. This article reviews the on-and off-label uses of hyaluronidase and presents several clinical algorithms detailing the effective and safe use of hyaluronidase to manage complications secondary to hyaluronic acid fillers.
AB - Soft-tissue augmentation has become an increasingly popular option for facial rejuvenation. Hyaluronic acid fillers are part of the most rapidly expanding segment of this market, largely because of their safe drug profile and temporary nature. Despite their good safety profile, they can and do have complications ranging from superficial placement, uneven placement, granulomatous reactions, and skin necrosis. This article reviews the on-and off-label uses of hyaluronidase and presents several clinical algorithms detailing the effective and safe use of hyaluronidase to manage complications secondary to hyaluronic acid fillers.
UR - http://www.scopus.com/inward/record.url?scp=84893543178&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84893543178&partnerID=8YFLogxK
U2 - 10.1097/PRS.0b013e3182a4c282
DO - 10.1097/PRS.0b013e3182a4c282
M3 - Article
C2 - 24469183
AN - SCOPUS:84893543178
SN - 0032-1052
VL - 133
SP - 127e-132e
JO - Plastic and Reconstructive Surgery
JF - Plastic and Reconstructive Surgery
IS - 2
ER -