Central Venous Pressure in Space

J. C. Buckey, F. A. Gaffney, L. D. Lane, B. D. Levine, D. E. Watenpaugh, C. G. Blomqvist

Research output: Contribution to journalLetterpeer-review

75 Scopus citations


To the Editor: When a person enters zero gravity, a large amount of fluid (1 to 2 liters) shifts toward the head. The response to this shift includes the principal cardiovascular effects of spaceflight – e.g., hypovolemia, dehydration, and postflight orthostatic intolerance1. On earth, a similar headward shift of fluid increases central venous pressure2; in space, however, peripheral antecubital venous pressure does not increase3,4. It is not known whether such peripheral measurements reflect central venous pressure. Only direct, continuous measurements recorded during a change from earth's gravity (1 g) to zero gravity can resolve these controversies…

Original languageEnglish (US)
Pages (from-to)1853-1854
Number of pages2
JournalNew England Journal of Medicine
Issue number25
StatePublished - Jun 24 1993

ASJC Scopus subject areas

  • Medicine(all)


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