Cell forces meet cell metabolism

Tadamoto Isogai, Jin Suk Park, Gaudenz Danuser

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Epithelial cells form energetically costly cell-cell adhesions in response to mechanical forces. How cells obtain their energy during this event is unclear. Activity of a key regulator of cell metabolism, the AMP-activated protein kinase (AMPK), is now shown to be mechanoresponsive, and thus can bridge adhesion mechanotransduction and energy homeostasis.

Original languageEnglish (US)
Pages (from-to)591-593
Number of pages3
JournalNature Cell Biology
Issue number6
StatePublished - May 31 2017

ASJC Scopus subject areas

  • Cell Biology


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