Epithelial cells form energetically costly cell-cell adhesions in response to mechanical forces. How cells obtain their energy during this event is unclear. Activity of a key regulator of cell metabolism, the AMP-activated protein kinase (AMPK), is now shown to be mechanoresponsive, and thus can bridge adhesion mechanotransduction and energy homeostasis.
|Original language||English (US)|
|Number of pages||3|
|Journal||Nature Cell Biology|
|State||Published - May 31 2017|
ASJC Scopus subject areas
- Cell Biology