Catastrophic brain injury after nicotine insecticide ingestion

Alexander J. Rogers, Larry D. Denk, Paul M. Wax

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Much attention has been paid to the long-term toxic and carcinogenic effects of nicotine-containing substances, particularly tobacco. Although rare, acute ingestions of large amounts of nicotine can produce rapid and dramatic toxicity. We present a case of an ingestion of a nicotine sulfate solution by a 15-year-old boy resulting in hypoxia and irreversible encephalopathy. The diagnosis of acute nicotine toxicity potentially could be delayed due to the fact that nicotine and cotinine are so commonly found on drug screens that they are considered "normal variants."

Original languageEnglish (US)
Pages (from-to)169-172
Number of pages4
JournalJournal of Emergency Medicine
Issue number2
StatePublished - Feb 2004


  • Brain injury
  • Nicotine
  • Pediatrics
  • Pesticides

ASJC Scopus subject areas

  • Emergency Medicine


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