CASMIL: A comprehensive software/toolkit for image-guided neurosurgeries

Gulsheen Kaur, Jun Tan, Mohammed Alam, Vipin Chaudhary, Dingguo Chen, Ming Dong, Hazem Eltahawy, Farshad Fotouhi, Christopher Gammage, Jason Gong, William Grosky, Murali Guthikonda, Jingwen Hu, Devkanak Jeyaraj, Xin Jin, Albert King, Joseph Landman, Jong Lee, Qing Hang Li, Hanping LufeiMichael Morse, Jignesh Patel, Ishwar Sethi, Weisong Shi, King Yang, Zhiming Zhang

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Background: CASMIL aims to develop a cost-effective and efficient approach to monitor and predict deformation during surgery, allowing accurate, and real-time intra-operative information to be provided reliably to the surgeon. Method: CASMIL is a comprehensive Image-guided Neurosurgery System with extensive novel features. It is an integration of various modules including rigid and non-rigid body co-registration (image-image, image-atlas, and image-patient), automated 3D segmentation, brain shift predictor, knowledge based query tools, intelligent planning, and augmented reality. One of the vital and unique modules is the Intelligent Planning module, which displays the best surgical corridor on the computer screen based on tumor location, captured surgeon knowledge, and predicted brain shift using patient specific Finite Element Model. Also, it has multi-level parallel computing to provide near real-time interaction with iMRI (Intra-operative MRI). In addition, it has been securely web-enabled and optimized for remote web and PDA access. Results: A version of this system is being used and tested using real patient data and is expected to be in use in the operating room at the Detroit Medical Center in the first half of 2006. Conclusion: CASMIL is currently under development and is targeted for minimally invasive surgeries. With minimal changes to the design, it can be easily extended and made available for other surgical procedures.

Original languageEnglish (US)
Pages (from-to)123-138
Number of pages16
JournalInternational Journal of Medical Robotics and Computer Assisted Surgery
Issue number2
StatePublished - Jun 2006
Externally publishedYes


  • Augmented reality
  • Brain shift
  • Computer-assisted surgery
  • Finite element model
  • Intelligent planning
  • Neurosurgery
  • Parallel computing in surgery

ASJC Scopus subject areas

  • Surgery
  • Biophysics
  • Computer Science Applications


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