Cardiac amyloidosis secondary to multiple myeloma

Thais C. Mussi; Gilberto Szarf; Pablo G.R. Furtado; Flavio Duarte; Edson Nakano; Rogério Pinetti; Denis Szejnfeld; Marcello F. Franco; Antonio Carlos Antonio; Sérgio A. Ajzen

doi:10.1016/j.ejrex.2010.04.011

Cardiac amyloidosis secondary to multiple myeloma

Thais C. Mussi, Gilberto Szarf, Pablo G.R. Furtado, Flavio Duarte, Edson Nakano, Rogério Pinetti, Denis Szejnfeld, Marcello F. Franco, Antonio Carlos Antonio, Sérgio A. Ajzen

Research output: Contribution to journal › Article › peer-review

Abstract

We report a case of a 51-year-old Caucasian man with progressive heart failure and multiple lytic lesions in the skull and long bones. The diagnosis of multiple myeloma and cardiac involvement by secondary amyloidosis was made, but the patient died despite treatment, and the diagnosis was confirmed at autopsy. Cardiac amyloidosis is clinically silent and when the symptoms appear, median survival is less than 1 year. The diagnosis of amyloidosis should be considered in any patient with multiple myeloma and heart failure, and the magnetic resonance imaging (MRI) can help to make this diagnosis.

Original language	English (US)
Pages (from-to)	e13-e16
Journal	European Journal of Radiology Extra
Volume	75
Issue number	1
DOIs	https://doi.org/10.1016/j.ejrex.2010.04.011
State	Published - Jul 2010
Externally published	Yes

Keywords

Cardiac amyloidosis
Magnetic resonance
Multiple myeloma
Myocardial late enhancement

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.ejrex.2010.04.011

Cite this

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title = "Cardiac amyloidosis secondary to multiple myeloma",

abstract = "We report a case of a 51-year-old Caucasian man with progressive heart failure and multiple lytic lesions in the skull and long bones. The diagnosis of multiple myeloma and cardiac involvement by secondary amyloidosis was made, but the patient died despite treatment, and the diagnosis was confirmed at autopsy. Cardiac amyloidosis is clinically silent and when the symptoms appear, median survival is less than 1 year. The diagnosis of amyloidosis should be considered in any patient with multiple myeloma and heart failure, and the magnetic resonance imaging (MRI) can help to make this diagnosis.",

keywords = "Cardiac amyloidosis, Magnetic resonance, Multiple myeloma, Myocardial late enhancement",

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T1 - Cardiac amyloidosis secondary to multiple myeloma

AU - Mussi, Thais C.

AU - Szarf, Gilberto

AU - Furtado, Pablo G.R.

AU - Duarte, Flavio

AU - Nakano, Edson

AU - Pinetti, Rogério

AU - Szejnfeld, Denis

AU - Franco, Marcello F.

AU - Antonio, Antonio Carlos

AU - Ajzen, Sérgio A.

PY - 2010/7

Y1 - 2010/7

N2 - We report a case of a 51-year-old Caucasian man with progressive heart failure and multiple lytic lesions in the skull and long bones. The diagnosis of multiple myeloma and cardiac involvement by secondary amyloidosis was made, but the patient died despite treatment, and the diagnosis was confirmed at autopsy. Cardiac amyloidosis is clinically silent and when the symptoms appear, median survival is less than 1 year. The diagnosis of amyloidosis should be considered in any patient with multiple myeloma and heart failure, and the magnetic resonance imaging (MRI) can help to make this diagnosis.

AB - We report a case of a 51-year-old Caucasian man with progressive heart failure and multiple lytic lesions in the skull and long bones. The diagnosis of multiple myeloma and cardiac involvement by secondary amyloidosis was made, but the patient died despite treatment, and the diagnosis was confirmed at autopsy. Cardiac amyloidosis is clinically silent and when the symptoms appear, median survival is less than 1 year. The diagnosis of amyloidosis should be considered in any patient with multiple myeloma and heart failure, and the magnetic resonance imaging (MRI) can help to make this diagnosis.

KW - Cardiac amyloidosis

KW - Magnetic resonance

KW - Multiple myeloma

KW - Myocardial late enhancement

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Cardiac amyloidosis secondary to multiple myeloma

Abstract

Keywords

ASJC Scopus subject areas

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