Burden of diagnostic radiation exposure in children with sickle cell disease

Courtney L. Vetter, George R. Buchanan, Charles T. Quinn

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Children with sickle cell disease (SCD) are repeatedly exposed to diagnostic radiation. We identified 938 children with SCD who had 9,246 radiographic tests. Mean number of tests/patient was 9.9 (95% CI: 8.9-10.9) over 8,817 patient-years. Mean rate was 1.5 tests/year (95% CI: 1.3-1.6). On average, a child with SCD will have 26.7 (95% CI: 24.1-29.3) radiographic tests by 18 years of age, and 5% will have ≥100 tests. Six percent have ≥3 CT scans, which may be associated with an increased risk of cancer. Strong consideration should be given to limiting the exposure of children with SCD to radiation. Pediatr Blood Cancer 2014;61:1322-1324.

Original languageEnglish (US)
Pages (from-to)1322-1324
Number of pages3
JournalPediatric Blood and Cancer
Issue number7
StatePublished - Jul 2014


  • Irradiation
  • Radiation
  • Radiograph
  • Radiology
  • Sickle cell disease

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology


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