Exposure of a variety of mono- and disubstituted ortho-alkenylarylboronic acids to NBS in THF/H2O under neutral conditions affords bromo-boronolactones, in some instances, with exceptional regiocontrol. The adducts, analogous to those formed by carboxylic acids, are shown to be useful synthetic intermediates.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of Organic Chemistry|
|State||Published - Oct 19 2001|
ASJC Scopus subject areas
- Organic Chemistry