Brain repair by endogenous progenitors

Genevieve M. Kruger; Sean J. Morrison

doi:10.1016/S0092-8674(02)00899-1

Brain repair by endogenous progenitors

Genevieve M. Kruger, Sean J. Morrison

Research output: Contribution to journal › Review article › peer-review

64 Scopus citations

Abstract

Stem cells within the adult brain can be stimulated by injury and growth factor treatment to replace damaged neurons, even neurons that are not normally generated in adults. Coupled with recent insights into the mechanism by which Nogo inhibits axonal regeneration, this discovery may inspire new treatments for central nervous system injuries and neurodegenerative diseases.

Original language	English (US)
Pages (from-to)	399-402
Number of pages	4
Journal	Cell
Volume	110
Issue number	4
DOIs	https://doi.org/10.1016/S0092-8674(02)00899-1
State	Published - Aug 23 2002

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/S0092-8674(02)00899-1

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title = "Brain repair by endogenous progenitors",

abstract = "Stem cells within the adult brain can be stimulated by injury and growth factor treatment to replace damaged neurons, even neurons that are not normally generated in adults. Coupled with recent insights into the mechanism by which Nogo inhibits axonal regeneration, this discovery may inspire new treatments for central nervous system injuries and neurodegenerative diseases.",

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AB - Stem cells within the adult brain can be stimulated by injury and growth factor treatment to replace damaged neurons, even neurons that are not normally generated in adults. Coupled with recent insights into the mechanism by which Nogo inhibits axonal regeneration, this discovery may inspire new treatments for central nervous system injuries and neurodegenerative diseases.

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Brain repair by endogenous progenitors

Abstract

ASJC Scopus subject areas

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