Biotin Deficiency: An Unusual Complication of Parenteral Alimentation

Donald M. Mock, Alfred A. Delorimer, William M. Liebman, Lawrence Sweetman, Herman Baker, Donald M. Mock

Research output: Contribution to journalArticlepeer-review

127 Scopus citations


BIOTIN deficiency has been documented in human beings only in association with prolonged ingestion of raw egg white. In this paper, we report that clinically important biotin deficiency occurred in a child with short-gut syndrome during parenteral alimentation. Case Report The clinical history and growth of this 12-month-old girl were normal until four months of age, when malrotation and midgut volvulus resulted in extensive infarction of the small and large bowel. After the initial bowel resection, her clinical course was complicated by anastomosis failure, peritoneal infection, and bowel obstruction. Ultimately, the patient retained only 30 cm of jejunum, 0.5 cm.  . .

Original languageEnglish (US)
Pages (from-to)820-823
Number of pages4
JournalNew England Journal of Medicine
Issue number14
StatePublished - Apr 2 1981
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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