Biomarkers in heart failure

Ravi V. Shah, Thomas J. Wang

Research output: Chapter in Book/Report/Conference proceedingChapter


The clinical diagnosis of heart failure (HF) relies primarily on signs and symptoms of congestion, complemented by radiographic and echocardiographic studies. Unfortunately, most physical and historical criteria for the diagnosis of HF (e.g., jugular venous distension, rales, peripheral edema, and dyspnea) are variably present and may only modestly increase the likelihood of a correct diagnosis (1,2). In the past decade, a number of circulating biomarkers have been identified that are elevated in individuals with cardiac overload or overt HF, raising the hope that measurement of these biomarkers could assist in acute diagnosis of HF, as well as the determination of prognosis.

Original languageEnglish (US)
Title of host publicationHeart Failure, Second Edition
PublisherCRC Press
Number of pages14
ISBN (Electronic)9781420077018
ISBN (Print)9781420076998
StatePublished - Jan 1 2012
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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