Bacteria as Specific Binding Agents for an Isotopic Assay of Serum Folate

M. S. McCall; J. D. White; E. P. Frenkel

doi:10.3181/00379727-134-34830

Bacteria as Specific Binding Agents for an Isotopic Assay of Serum Folate

M. S. McCall, J. D. White, E. P. Frenkel

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Saturation analysis or competitive inhibition utilizing bacteria (L. casei) as the specific binder permitted the measurement of serum folate. Unlike conventional microbiologic techniques, organism growth rate was not determined. This new “radiomicrobiologic” approach quantitated serum folate by competitive binding of tritiated folic acid during the early “lag” phase of bacterial growth.

Original language	English (US)
Pages (from-to)	536-538
Number of pages	3
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	134
Issue number	2
DOIs	https://doi.org/10.3181/00379727-134-34830
State	Published - Jun 1970

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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title = "Bacteria as Specific Binding Agents for an Isotopic Assay of Serum Folate",

abstract = "Saturation analysis or competitive inhibition utilizing bacteria (L. casei) as the specific binder permitted the measurement of serum folate. Unlike conventional microbiologic techniques, organism growth rate was not determined. This new “radiomicrobiologic” approach quantitated serum folate by competitive binding of tritiated folic acid during the early “lag” phase of bacterial growth.",

author = "McCall, {M. S.} and White, {J. D.} and Frenkel, {E. P.}",

year = "1970",

month = jun,

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AU - McCall, M. S.

AU - White, J. D.

AU - Frenkel, E. P.

PY - 1970/6

Y1 - 1970/6

N2 - Saturation analysis or competitive inhibition utilizing bacteria (L. casei) as the specific binder permitted the measurement of serum folate. Unlike conventional microbiologic techniques, organism growth rate was not determined. This new “radiomicrobiologic” approach quantitated serum folate by competitive binding of tritiated folic acid during the early “lag” phase of bacterial growth.

AB - Saturation analysis or competitive inhibition utilizing bacteria (L. casei) as the specific binder permitted the measurement of serum folate. Unlike conventional microbiologic techniques, organism growth rate was not determined. This new “radiomicrobiologic” approach quantitated serum folate by competitive binding of tritiated folic acid during the early “lag” phase of bacterial growth.

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AN - SCOPUS:0014803575

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ER -

Bacteria as Specific Binding Agents for an Isotopic Assay of Serum Folate

Abstract

ASJC Scopus subject areas

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