Abstract
Gut cells are exposed to diverse insults that necessitate their replacement from a stem cell pool balancing differentiation and proliferation. In this issue of Developmental Cell, Zhang and colleagues (2019) show autophagy-mediated regulation of EGFR signaling cell autonomously controls intestinal stem cell proliferation, with implications for human colorectal cancer development.
Original language | English (US) |
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Pages (from-to) | 499-500 |
Number of pages | 2 |
Journal | Developmental cell |
Volume | 49 |
Issue number | 4 |
DOIs | |
State | Published - May 20 2019 |
ASJC Scopus subject areas
- Molecular Biology
- General Biochemistry, Genetics and Molecular Biology
- Developmental Biology
- Cell Biology