Autonomic dysfunction in Parkinson's disease

Richard B. Dewey

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations


Symptoms of autonomic dysfunction develop in the majority of patients with PD. The severity of autonomic symptoms is generally mild in PD patients compared with MSA patients, but the symptoms can be severely disabling in some PD patients. Evidence suggests that the neurodegeneration of PD is involved in the genesis of autonomic symptoms, but other conditions and drug side effects must be considered. Treatment of autonomic dysfunction should begin with nonpharmacologic measures and progress to pharmacotherapy in cases where symptoms remain disabling. Early recognition and management of the symptoms of autonomic dysfunction in PD patients is important for preserving QOL and reducing the risk of adverse events.

Original languageEnglish (US)
Pages (from-to)S127-S139
JournalNeurologic Clinics
Issue number3 SUPPL.
StatePublished - Aug 2004

ASJC Scopus subject areas

  • Clinical Neurology


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