Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy

Kartik R. Kumar; Swati N. Mandleywala; Mark S. Link

doi:10.1016/j.ccep.2015.03.002

Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy

Kartik R. Kumar, Swati N. Mandleywala, Mark S. Link

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease caused by mutations in genes coding for cardiac sarcomeres. HCM is the most common inherited heart disease, with a prevalence of 0.2%. There are multiple genetic variants that cause pleomorphic clinical attributes and disease characterized by myocardial disarray and myocardial hypertrophy. Patients are at an increased risk of atrial and ventricular arrhythmias. Management of these arrhythmias is complex. Atrial fibrillation is associated with increased mortality and thromboembolism. Ventricular arrhythmias are life threatening and best treated with an implantable defibrillator.

Original language	English (US)
Pages (from-to)	173-186
Number of pages	14
Journal	Cardiac Electrophysiology Clinics
Volume	7
Issue number	2
DOIs	https://doi.org/10.1016/j.ccep.2015.03.002
State	Published - Jun 1 2015

Keywords

Arrhythmias
Atrial fibrillation
Electrophysiology
Hypertrophic cardiomyopathy
Risk factors
Ventricular fibrillation

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1016/j.ccep.2015.03.002

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title = "Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy",

abstract = "Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease caused by mutations in genes coding for cardiac sarcomeres. HCM is the most common inherited heart disease, with a prevalence of 0.2%. There are multiple genetic variants that cause pleomorphic clinical attributes and disease characterized by myocardial disarray and myocardial hypertrophy. Patients are at an increased risk of atrial and ventricular arrhythmias. Management of these arrhythmias is complex. Atrial fibrillation is associated with increased mortality and thromboembolism. Ventricular arrhythmias are life threatening and best treated with an implantable defibrillator.",

keywords = "Arrhythmias, Atrial fibrillation, Electrophysiology, Hypertrophic cardiomyopathy, Risk factors, Ventricular fibrillation",

author = "Kumar, {Kartik R.} and Mandleywala, {Swati N.} and Link, {Mark S.}",

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T1 - Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy

AU - Kumar, Kartik R.

AU - Mandleywala, Swati N.

AU - Link, Mark S.

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease caused by mutations in genes coding for cardiac sarcomeres. HCM is the most common inherited heart disease, with a prevalence of 0.2%. There are multiple genetic variants that cause pleomorphic clinical attributes and disease characterized by myocardial disarray and myocardial hypertrophy. Patients are at an increased risk of atrial and ventricular arrhythmias. Management of these arrhythmias is complex. Atrial fibrillation is associated with increased mortality and thromboembolism. Ventricular arrhythmias are life threatening and best treated with an implantable defibrillator.

AB - Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease caused by mutations in genes coding for cardiac sarcomeres. HCM is the most common inherited heart disease, with a prevalence of 0.2%. There are multiple genetic variants that cause pleomorphic clinical attributes and disease characterized by myocardial disarray and myocardial hypertrophy. Patients are at an increased risk of atrial and ventricular arrhythmias. Management of these arrhythmias is complex. Atrial fibrillation is associated with increased mortality and thromboembolism. Ventricular arrhythmias are life threatening and best treated with an implantable defibrillator.

KW - Arrhythmias

KW - Atrial fibrillation

KW - Electrophysiology

KW - Hypertrophic cardiomyopathy

KW - Risk factors

KW - Ventricular fibrillation

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JO - Cardiac Electrophysiology Clinics

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ER -

Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy

Abstract

Keywords

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