Assessment of Preterm Birth Risk by Collagen Scoring with Polarized Light in Mice Model of Pregnancy

Hee Ryung Lee, Ilyas Saytashev, Vinh Nguyen Du Le, Mala Mahendroo, Jessica Ramella-Roman, Tatiana Novikova

Research output: Contribution to journalConference articlepeer-review

Abstract

Polarimetric images of thin histological sections of uterine cervices from nonpregnant and pregnant mice were recorded with Mueller matrix microscope. The results of two-Gaussian fit of the distributions of linear scalar retardance of cervical tissue demonstrated that imaging Mueller polarimetry may quantify the evolution of cervical collagen with pregnancy. It opens the avenue for a fast and non-contact polarimetric assessment of the preterm birth risk.

Original languageEnglish (US)
Article numberTM4B.4
JournalOptics InfoBase Conference Papers
StatePublished - 2022
EventClinical and Translational Biophotonics, Translational 2022 - Fort Lauderdale, United States
Duration: Apr 24 2022Apr 27 2022

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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