TY - JOUR
T1 - Assessment of Mortality after Long-Term Follow-Up of Patients with Community-Acquired Pneumonia
AU - Mortensen, Eric M.
AU - Kapoor, Wishwa N.
AU - Chang, Chung Chou H
AU - Fine, Michael J.
N1 - Funding Information:
Data for this project were obtained as part of the Pneumonia Patient Outcomes Research Team project funded by the Agency for Healthcare Research and Quality (grant RO1HSO6468).
Funding Information:
Financial support: Agency for Healthcare Research and Quality National Research Service Award (grant F32 HS00135 to E.M.M.) and National Institute of Allergy and Infectious Diseases (K24 career development award to M.J.F.).
PY - 2003/12/15
Y1 - 2003/12/15
N2 - Although studies have assessed short-term mortality among patients with community-acquired pneumonia, there is limited data on prognosis and risk factors that affect long-term mortality. The mortality among patients enrolled at 4 sites of the Pneumonia Patient Outcome Research Team cohort study who survived at least 90 days after presentation to the hospital was compared with that among age-matched control subjects. Overall, 1419 of 1555 patients survived for >90 days, with a mean follow-up period of 5.9 years. There was significantly higher long-term mortality among patients with pneumonia than among age-matched controls. Factors significantly associated with long-term mortality were age (stratified by decade), do-not-resuscitate status, poor nutritional status, pleural effusion, glucocorticoid use, nursing home residence, high school graduation level or less, male sex, preexisting comorbid illnesses, and the lack of feverishness. This study demonstrates that there is significantly higher long-term mortality among patients with pneumonia than among age-matched controls and that long-term mortality largely is not affected by acute physiologic derangements.
AB - Although studies have assessed short-term mortality among patients with community-acquired pneumonia, there is limited data on prognosis and risk factors that affect long-term mortality. The mortality among patients enrolled at 4 sites of the Pneumonia Patient Outcome Research Team cohort study who survived at least 90 days after presentation to the hospital was compared with that among age-matched control subjects. Overall, 1419 of 1555 patients survived for >90 days, with a mean follow-up period of 5.9 years. There was significantly higher long-term mortality among patients with pneumonia than among age-matched controls. Factors significantly associated with long-term mortality were age (stratified by decade), do-not-resuscitate status, poor nutritional status, pleural effusion, glucocorticoid use, nursing home residence, high school graduation level or less, male sex, preexisting comorbid illnesses, and the lack of feverishness. This study demonstrates that there is significantly higher long-term mortality among patients with pneumonia than among age-matched controls and that long-term mortality largely is not affected by acute physiologic derangements.
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U2 - 10.1086/379712
DO - 10.1086/379712
M3 - Article
C2 - 14689342
AN - SCOPUS:0347288599
SN - 1058-4838
VL - 37
SP - 1617
EP - 1624
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 12
ER -