Assessing the irritation potential of Eye area products in the human eye

Robertb Drotman, James P. Mc Culley, Thomas J. Stephens, Alice Matoba, Richard F. Gunst

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Current safety testing programs for consumer products generally include a test to evaluate potential eye damage by assessing objective irritation in the conjunctivum, iris, or cornea. However, the potential for a product to cause eye discomfort in the form of subjective irritation through burning, itching, or tearing cannot be measured by standard eye safety tests. A protocol has been developed to test for these subjective irritation responses. Results indicate that, with the application of proper statistical treatment, differences in factors measuring subjective irritation of the eyes by different test materials can be detected.

Original languageEnglish (US)
Pages (from-to)3-11
Number of pages9
JournalCutaneous and Ocular Toxicology
Issue number1
StatePublished - 1985

ASJC Scopus subject areas

  • Toxicology


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