Approach to the patient with recurrent nephrolithiasis

Mary Ann Cameron, Charles Y C Pak

Research output: Contribution to journalReview articlepeer-review


Although recurring nephrolithiasis may not be as common as single-episode disease, it poses greater problems to the patient's daily lifestyle and general future health status. The general need for an adequate history, examination, and radiological assessment is acknowledged, but a more intensive investigative and management approach is required. Investigations for secondary causes are paramount and may lead to identification of unusual metabolic abnormalities and specific therapies. Such medical approaches entail consideration of dietary adjustments to lower the urinary excretion of components of the renal stones, pharmacological therapies to modulate urinary constituents and limit renal stone risk, and monitoring efficacy of the therapy over time. This approach will prevent significant deterioration of renal function and other serious metabolic consequences.

Original languageEnglish (US)
Pages (from-to)279-289
Number of pages11
JournalClinical Reviews in Bone and Mineral Metabolism
Issue number3
StatePublished - 2004


  • Diagnosis
  • Pathophysiology
  • Recurrent nephrolithiasis
  • Therapy

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine
  • Endocrinology


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