@inproceedings{878c75945a354cd8a52ba880d0685bb6,
title = "Application of laser speckle contrast image in the evaluation of arthritis animal model",
abstract = "Arthritis is a chronic inflammatory disease that induces potentially damaging and commonly disabling. Various imaging modalities have been used for the evaluation of arthritis. This study aimed to investigate the feasibility of laser speckle contrast image (LSCI) in the evaluation of the severity and early stage of arthritis in animal model. Arthritis was induced on mouse foot and evaluated by a trained expert and the LSCI. The arthritis severity was quantitatively evaluated by speckle index (SI) computed from LSCI. In visual inspection by an expert, it was difficult to evaluate the arthritis because there was no noticeable different between control mouse group (CMG) and arthritis mouse group (AMG) in erythema. However, arthritis was easily evaluated by significant SI different between the CMG and AMG. In addition, the LSCI also successfully evaluated the early stage of arthritis, presenting different SI distribution depending on lesion.",
author = "Taeyoon Son and Jang, {Won Hyuk} and Jihoon Park and Yoon, {Hyung Ju} and Jeon Lee and Kim, {Wan Uk} and Byungjo Jung",
year = "2013",
doi = "10.1117/12.2004013",
language = "English (US)",
isbn = "9780819493347",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Photonic Therapeutics and Diagnostics IX",
note = "Photonic Therapeutics and Diagnostics IX ; Conference date: 02-02-2013 Through 07-02-2013",
}