TY - JOUR
T1 - Antimicrobial susceptibility patterns (antibiograms) as an aid in differentiating citrobacter species
AU - Southern, P. M.
AU - Bagby, M. K.
PY - 1977/1/1
Y1 - 1977/1/1
N2 - The hydrogen sulfide-negative Citrobacter group represents a taxonomic problem. Various investigators have proposed such designations as Padlewskia, Levinea, atypical Enterobacter cloacae, H2S-negative variants of Citrobacter, Citrobacter koseri and Citrobacter diversus. This problem has been investigated with emphasis on antibiograms as a means of discrimination. Clinical isolates fitting the designation Citrobacter were studied and, using the criteria of Ewing and Davis, separated into two groups: C. diversus (40 strains) or C. freundii (25 strains). Susceptibilities to ampicillin, carbenicillin, cefazolin, cephaloridine and cephalothin were determined by the agar-dilution method. C. diversus strains were resistant to 8 μg/ml ampicillin (97.5%) and 32 μg/ml carbenicillin (87.5%), and were susceptible to 8 μg/ml cephalosporins (≥90%). C. freundii strains were moderately susceptible to 8 μg/ml ampicillin (25%) and susceptible to 8 μg/ml carbenicillin (92%), and were resistant to 8 μg/ml cephalosporins (≥92%). Using these data one can separate C. diversus from C. freundii with 90% accuracy.
AB - The hydrogen sulfide-negative Citrobacter group represents a taxonomic problem. Various investigators have proposed such designations as Padlewskia, Levinea, atypical Enterobacter cloacae, H2S-negative variants of Citrobacter, Citrobacter koseri and Citrobacter diversus. This problem has been investigated with emphasis on antibiograms as a means of discrimination. Clinical isolates fitting the designation Citrobacter were studied and, using the criteria of Ewing and Davis, separated into two groups: C. diversus (40 strains) or C. freundii (25 strains). Susceptibilities to ampicillin, carbenicillin, cefazolin, cephaloridine and cephalothin were determined by the agar-dilution method. C. diversus strains were resistant to 8 μg/ml ampicillin (97.5%) and 32 μg/ml carbenicillin (87.5%), and were susceptible to 8 μg/ml cephalosporins (≥90%). C. freundii strains were moderately susceptible to 8 μg/ml ampicillin (25%) and susceptible to 8 μg/ml carbenicillin (92%), and were resistant to 8 μg/ml cephalosporins (≥92%). Using these data one can separate C. diversus from C. freundii with 90% accuracy.
UR - http://www.scopus.com/inward/record.url?scp=0017331506&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017331506&partnerID=8YFLogxK
U2 - 10.1093/ajcp/67.2.187
DO - 10.1093/ajcp/67.2.187
M3 - Article
C2 - 836626
AN - SCOPUS:0017331506
SN - 0002-9173
VL - 67
SP - 187
EP - 189
JO - American journal of clinical pathology
JF - American journal of clinical pathology
IS - 2
ER -