Abstract
Immunotoxins are protein molecules composed of monoclonal antibodies linked covalently to either peptide toxins or polypeptides related to toxins. These molecules can be used in the therapy of a number of malignant diseases including lymphoma, leukemia, and solid tumors. They can be used to prevent graft-versus-host disease or rejection in transplanted organs, such as bone marrow and pancreas. The design and development of these molecules, as well as a clinical development plan, will be discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 437-446 |
| Number of pages | 10 |
| Journal | Journal of Biological Response Modifiers |
| Volume | 4 |
| Issue number | 5 |
| State | Published - Oct 1985 |
Keywords
- Immunotoxin
ASJC Scopus subject areas
- Immunology
- Pharmacology
- Cancer Research