Anti-inflammatory and immunosuppressive drugs and reproduction

Monika Øtensen, Munther Khamashta, Michael Lockshin, Ann Parke, Antonio Brucato, Howard Carp, Andrea Doria, Raj Rai, Pierluigi Meroni, Irene Cetin, Ronald Derksen, Ware Branch, Mario Motta, Caroline Gordon, Guillermo Ruiz-Irastorza, Arsenio Spinillo, Deborah I Friedman, Rolando Cimaz, Andrew Czeizel, Jean Charles PietteRicard Cervera, Roger A. Levy, Maurizio Clementi, Sara De Carolis, Michelle Petri, Yehuda Shoenfeld, David Faden, Guido Valesini, Angela Tincani

Research output: Contribution to journalReview articlepeer-review

445 Scopus citations


Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed where data were available. Recommendations for drug treatment during pregnancy and lactation are given.

Original languageEnglish (US)
Article number1957
JournalArthritis Research and Therapy
Issue number3
StatePublished - Jun 2006

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology


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