Analysis of [11C]Choline and [13N]Ammonia using a single HPIC method

Huailei Jiang, Ping Fang, Mark S. Jacobson, Manoj K. Jain, Hancheng Cai

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A single HPIC method was developed and validated for the analysis of both [11C]Choline and [13N]Ammonia with the same setup. The HPIC system suitability tests were performed and [11C]Choline and [13N]Ammonia were used to verify their performance on this HPIC method. The HPIC setup and method provides qualitative and quantitative analysis information of [11C]Choline and [13N]Ammonia. The data suggested this HPIC method is validated for determining radiochemical/chemical purity and radiochemical identity of [11C]Choline and [13N]Ammonia products in CGMP compliant manufacturing process.

Original languageEnglish (US)
Article number109560
JournalApplied Radiation and Isotopes
StatePublished - Feb 2021
Externally publishedYes


  • HPIC
  • Method validation
  • PET
  • Quality control
  • [C]Choline
  • [N]Ammonia

ASJC Scopus subject areas

  • Radiation


Dive into the research topics of 'Analysis of [11C]Choline and [13N]Ammonia using a single HPIC method'. Together they form a unique fingerprint.

Cite this