An evaluation of the acidified glycerol lysis test

C. J. Rutherford; B. F. Postlewaight; M. Hallowes

doi:10.1111/j.1365-2141.1986.tb07501.x

An evaluation of the acidified glycerol lysis test

C. J. Rutherford, B. F. Postlewaight, M. Hallowes

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Abstract

The acidified glycerol lysis test (AGLT), as a screening procedure for spherocytosis, has been assessed for sensitivity and specificity. AGLT identified 24 of 26 subjects with hereditary spherocytosis and produced 19 abnormal AGLTs out of a total of 52 normal blood donors. The claims for the test as being both 100% sensitive and specific could not be confirmed.

Original language	English (US)
Pages (from-to)	119-121
Number of pages	3
Journal	British Journal of Haematology
Volume	63
Issue number	1
DOIs	https://doi.org/10.1111/j.1365-2141.1986.tb07501.x
State	Published - May 1986

ASJC Scopus subject areas

Hematology

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10.1111/j.1365-2141.1986.tb07501.x

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title = "An evaluation of the acidified glycerol lysis test",

abstract = "The acidified glycerol lysis test (AGLT), as a screening procedure for spherocytosis, has been assessed for sensitivity and specificity. AGLT identified 24 of 26 subjects with hereditary spherocytosis and produced 19 abnormal AGLTs out of a total of 52 normal blood donors. The claims for the test as being both 100% sensitive and specific could not be confirmed.",

author = "Rutherford, {C. J.} and Postlewaight, {B. F.} and M. Hallowes",

year = "1986",

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AU - Hallowes, M.

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AB - The acidified glycerol lysis test (AGLT), as a screening procedure for spherocytosis, has been assessed for sensitivity and specificity. AGLT identified 24 of 26 subjects with hereditary spherocytosis and produced 19 abnormal AGLTs out of a total of 52 normal blood donors. The claims for the test as being both 100% sensitive and specific could not be confirmed.

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An evaluation of the acidified glycerol lysis test

Abstract

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