Alkylthioether synthesis via imidazole mediated Mitsunobu condensation

J R Falck, Jing Yu Lai, Su Dong Cho, Jurong Yu

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Unsymmetric alkylthioethers can be prepared from aliphatic thiols and unhindered alcohols under modified Mitsunobu conditions using trimethylphosphine/1,1'-(azodicarbonyl)dipiperdine (ADDP) in the presence of imidazote (2 equivalents).

Original languageEnglish (US)
Pages (from-to)2903-2906
Number of pages4
JournalTetrahedron Letters
Issue number15
StatePublished - Apr 9 1999


  • Condensation
  • Intidazole
  • Mitsunobu
  • Thioethers

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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