@inbook{647a983264aa4ddc8025afd01141d0e4,
title = "Advances in biomarker development in acetaminophen toxicity",
abstract = "Acetaminophen liver injury is the most common cause of acute liver injury in the United States and several other countries. Diagnosis of acetaminophen-induced acute liver injury in the clinic is challenging due to the lack of validated and specific biomarkers. The following chapter provides an overview of recent advances evaluating candidate biomarkers in development for acetaminophen acute liver injury. Relationships of biomarkers to mechanisms of acetaminophen toxicity and their potential role in confirming the diagnosis and/or predicting evolving toxicity are addressed.",
keywords = "Acetaminophen, Biomarker, Hepatotoxicity, Immunoassay, Liver",
author = "James, {Laura P.} and McGill, {Mitchell R.} and Roberts, {Dean W.} and Hinson, {Jack A.} and Lee, {William M.}",
note = "Funding Information: Dr. James, Hinson and Roberts are recipients of grant R42 DK079387 from the National Institute of Diabetes and Digestive Diseases. Dr. McGill is the recipient of a Pinnacle Research Award from the American Association for the Study of Liver Diseases (AASLD) Foundation. Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
doi = "10.1016/bs.acc.2020.02.002",
language = "English (US)",
series = "Advances in Clinical Chemistry",
publisher = "Academic Press Inc.",
booktitle = "Advances in Clinical Chemistry",
}