Adolescent–Parent Dyadic Retention in an Interview Study and Changes in Willingness to Participate in a Hypothetical Microbicide Safety Study

Jenny K.R. Francis, Ariel M. de Roche, Christine Mauro, Sara E. Landers, Jane Chang, Marina Catallozzi, Carmen Radecki Breitkopf, Susan L. Rosenthal

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Study Objective: In this study we describe adolescent and parent retention and changes in willingness to participate (WTP) in research among adolescents, parents, and adolescent–parent dyads. Design and Setting: Adolescent–parent dyads were recruited to participate in a longitudinal study to assess research participation attitudes using simultaneous individual interviews of the adolescent and parent with a return visit 1 year later using the same interview. Participants: Adolescents (14-17 years old) and their parents. Interventions: None. Main Outcome Measures: The relationship between participant characteristics and dyad retention was assessed. WTP was measured on a Likert scale and dichotomized (willing/unwilling) to assess changes in WTP attitudes over time for adolescents, parents, and dyads. Results: Eighty-three percent of the 300 dyads were retained. Dyads in which there was successful contact with the parent before follow-up were more likely to be retained (odds ratio, 4.88; 95% confidence interval, 2.57-9.26). For adolescents at baseline, 59% were willing to participate and 55% were willing to participate at follow-up (McNemar S = 0.91; P =.34). For parents at baseline, 51% were willing to participate and 57% were willing to participate at follow-up (McNemar S = 5.12; P =.02). For dyads at baseline, 57% were concordant (in either direction) and 70% of dyads were concordant at follow-up (McNemar S = 10.56; P =.001). Conclusion: Over 1 year, parent contact might positively influence successful adolescent retention. Parents become more willing to let their adolescents participate over time, with dyads becoming more concordant about research participation.

Original languageEnglish (US)
Pages (from-to)592-596
Number of pages5
JournalJournal of pediatric and adolescent gynecology
Issue number6
StatePublished - Dec 2018


  • Adolescent research participation
  • Clinical trials
  • Parent communication
  • Sexually transmitted infections
  • Topical microbicides

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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