Acute tubulointerstitial nephritis

Research output: Contribution to journalReview articlepeer-review

59 Scopus citations


Acute tubulointerstitial nephritis (ATIN) is a common disorder characterized by a spectrum of clinical manifestations ranging from asymptomatic urinary abnormalities to acute oliguric renal failure. Tubular dysfunction out of proportion to the degree of renal failure is an important clue to the diagnosis. This review describes its pathogenesis, pathophysiology, diagnosis, differential diagnosis and therapy, emphasizing the drug-induced form of ATIN.

Original languageEnglish (US)
Pages (from-to)392-410
Number of pages19
JournalAmerican Journal of the Medical Sciences
Issue number6
StatePublished - Jan 1 1990


  • Acute renal failure
  • Drugs
  • Hyperkalemic hyperchloremic metabolic acidosis
  • Tubulointerstitial nephritis

ASJC Scopus subject areas

  • Medicine(all)


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