Acute Liver Failure

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Rapid deterioration of hepatic function, characterized by coagulopathy and mental status changes, defines acute liver failure. There are numerous causes of acute liver failure which vary by geographic region. Survival depends on rapid diagnosis, treatment of the underlying aetiology if available and aggressive intensive care. Cerebral oedema, intracranial hypertension, metabolic derangements, bleeding and infection are common complications. The advent of liver transplantation has improved outcomes but mortality remains high despite medical advances.

Original languageEnglish (US)
Title of host publicationSherlock's Diseases of the Liver and Biliary System, 12th Edition
Number of pages24
ISBN (Print)9781405134897
StatePublished - May 5 2011


  • Coagulopathy
  • Complication
  • Encephalopathy
  • Fulminant hepatitis
  • Intensive care
  • Mental status

ASJC Scopus subject areas

  • Medicine(all)


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