Acute Liver Failure

Shannan R. Tujios; William M. Lee

doi:10.1002/9781444341294.ch5

Acute Liver Failure

Shannan R. Tujios, William M. Lee

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Rapid deterioration of hepatic function, characterized by coagulopathy and mental status changes, defines acute liver failure. There are numerous causes of acute liver failure which vary by geographic region. Survival depends on rapid diagnosis, treatment of the underlying aetiology if available and aggressive intensive care. Cerebral oedema, intracranial hypertension, metabolic derangements, bleeding and infection are common complications. The advent of liver transplantation has improved outcomes but mortality remains high despite medical advances.

Original language	English (US)
Title of host publication	Sherlock's Diseases of the Liver and Biliary System, 12th Edition
Publisher	Wiley-Blackwell
Pages	70-93
Number of pages	24
ISBN (Print)	9781405134897
DOIs	https://doi.org/10.1002/9781444341294.ch5
State	Published - May 5 2011

Keywords

Coagulopathy
Complication
Encephalopathy
Fulminant hepatitis
Intensive care
Mental status

ASJC Scopus subject areas

Medicine(all)

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10.1002/9781444341294.ch5

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AU - Lee, William M.

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AB - Rapid deterioration of hepatic function, characterized by coagulopathy and mental status changes, defines acute liver failure. There are numerous causes of acute liver failure which vary by geographic region. Survival depends on rapid diagnosis, treatment of the underlying aetiology if available and aggressive intensive care. Cerebral oedema, intracranial hypertension, metabolic derangements, bleeding and infection are common complications. The advent of liver transplantation has improved outcomes but mortality remains high despite medical advances.

KW - Coagulopathy

KW - Complication

KW - Encephalopathy

KW - Fulminant hepatitis

KW - Intensive care

KW - Mental status

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BT - Sherlock's Diseases of the Liver and Biliary System, 12th Edition

PB - Wiley-Blackwell

ER -

Acute Liver Failure

Abstract

Keywords

ASJC Scopus subject areas

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