Acquired cutis laxa associated with heavy chain deposition disease

Cynthia R. Harrington, Tracy C. Beswick, Joseph S. Susa, Amit G. Pandya

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Acquired cutis laxa (generalized acquired elastolysis) is a condition of unknown etiology characterized by a degeneration of elastic fibers in the skin, resulting in laxity with reduced elastic recoil. We describe a patient with acquired cutis laxa associated with an underlying heavy chain deposition disease. Direct immunofluorescence testing of lesional skin demonstrated immunoglobulin G deposition on elastic fibers, suggesting that in some cases, cutis laxa may have an immune-mediated etiopathogenesis.

Original languageEnglish (US)
Pages (from-to)S99-S101
JournalJournal of the American Academy of Dermatology
Issue number5 SUPPL.
StatePublished - Nov 2008

ASJC Scopus subject areas

  • Dermatology


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