A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast

Michael A. White; Peter Detloff; Micheline Strand; Thomas D. Petes

doi:10.1007/BF00318468

A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast

Michael A. White, Peter Detloff, Micheline Strand, Thomas D. Petes

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

Several investigators have reported that transcription stimulates some types of mitotic recombination in the yeast Saccharomyces cerevisiae. We find that mutations that reduce the rate of trancription of the yeast HIS4 gene in vegetative cells reduce the frequency of mitotic, but not meiotic, recombination events.

Original language	English (US)
Pages (from-to)	109-116
Number of pages	8
Journal	Current Genetics
Volume	21
Issue number	2
DOIs	https://doi.org/10.1007/BF00318468
State	Published - Feb 1992

Keywords

Gene conversion
Recombination
Transcription
Yeast

ASJC Scopus subject areas

Genetics

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10.1007/BF00318468

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title = "A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast",

abstract = "Several investigators have reported that transcription stimulates some types of mitotic recombination in the yeast Saccharomyces cerevisiae. We find that mutations that reduce the rate of trancription of the yeast HIS4 gene in vegetative cells reduce the frequency of mitotic, but not meiotic, recombination events.",

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AU - White, Michael A.

AU - Detloff, Peter

AU - Strand, Micheline

AU - Petes, Thomas D.

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AB - Several investigators have reported that transcription stimulates some types of mitotic recombination in the yeast Saccharomyces cerevisiae. We find that mutations that reduce the rate of trancription of the yeast HIS4 gene in vegetative cells reduce the frequency of mitotic, but not meiotic, recombination events.

KW - Gene conversion

KW - Recombination

KW - Transcription

KW - Yeast

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ER -

A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast

Abstract

Keywords

ASJC Scopus subject areas

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