TY - JOUR
T1 - A prolonged nursery epidemic associated with a newly recognized type of group A streptococcus
AU - Nelson, John D.
AU - Dillon, Hugh C.
AU - Howard, Jorge B.
PY - 1976/11
Y1 - 1976/11
N2 - During a six-month period 69 infants in a newborn nursery were colonized with group A streptococci. Fifty-one had omphalitis, two infected circumcision wounds, and one each had meningitis, primary peritonitis, and conjunctivitis. Thirteen infants were asymptomatically colonized. Control of the epidemic was difficult. Benzathine penicillin prophylaxis to all infants suppressed active infection but did not eradicate asymptomatic colonization of the umbilical cord. Triple dye treatment of the umbilical cord plus benzathine penicillin prophylaxis eradicated the infection from the nursery. The epidemic streptococcus was a newly recognized "skin strain", provisional type strain 5656-S, not previously known to cause epidemic disease or serious systemic infections.
AB - During a six-month period 69 infants in a newborn nursery were colonized with group A streptococci. Fifty-one had omphalitis, two infected circumcision wounds, and one each had meningitis, primary peritonitis, and conjunctivitis. Thirteen infants were asymptomatically colonized. Control of the epidemic was difficult. Benzathine penicillin prophylaxis to all infants suppressed active infection but did not eradicate asymptomatic colonization of the umbilical cord. Triple dye treatment of the umbilical cord plus benzathine penicillin prophylaxis eradicated the infection from the nursery. The epidemic streptococcus was a newly recognized "skin strain", provisional type strain 5656-S, not previously known to cause epidemic disease or serious systemic infections.
UR - http://www.scopus.com/inward/record.url?scp=0017109497&partnerID=8YFLogxK
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U2 - 10.1016/S0022-3476(76)80809-8
DO - 10.1016/S0022-3476(76)80809-8
M3 - Article
C2 - 789841
AN - SCOPUS:0017109497
SN - 0022-3476
VL - 89
SP - 792
EP - 796
JO - The Journal of pediatrics
JF - The Journal of pediatrics
IS - 5
ER -