A magnetic resonance image study of age-related changes in human putamen nuclei

W. M. McDonald; M. Husain; P. M. Doraiswamy; G. Figiel; O. Boyko; K. R R Krishnan

doi:10.1097/00001756-199101000-00014

A magnetic resonance image study of age-related changes in human putamen nuclei

W. M. McDonald, M. Husain, P. M. Doraiswamy, G. Figiel, O. Boyko, K. R R Krishnan

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42 Scopus citations

Abstract

Putamen nuclei were assessed in 36 normal volunteers using magnetic resonance imaging and a systematic sampling method. There was a significant decrease in the volume of the putamen nuclei with advancing age (r = —0.74, p < 0.0001), and an associated decline in the volume of the caudate nuclei (r = 0.60, p < 0.0001). The implications of these findings in age-associated motor abnormalities are discussed.

Original language	English (US)
Pages (from-to)	57-60
Number of pages	4
Journal	NeuroReport
Volume	2
Issue number	1
DOIs	https://doi.org/10.1097/00001756-199101000-00014
State	Published - Jan 1991

Keywords

Age-related changes
Magnetic resonance image
Putamen nuclei
Stereology

ASJC Scopus subject areas

General Neuroscience

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10.1097/00001756-199101000-00014

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AU - Husain, M.

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AU - Boyko, O.

AU - Krishnan, K. R R

PY - 1991/1

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N2 - Putamen nuclei were assessed in 36 normal volunteers using magnetic resonance imaging and a systematic sampling method. There was a significant decrease in the volume of the putamen nuclei with advancing age (r = —0.74, p < 0.0001), and an associated decline in the volume of the caudate nuclei (r = 0.60, p < 0.0001). The implications of these findings in age-associated motor abnormalities are discussed.

AB - Putamen nuclei were assessed in 36 normal volunteers using magnetic resonance imaging and a systematic sampling method. There was a significant decrease in the volume of the putamen nuclei with advancing age (r = —0.74, p < 0.0001), and an associated decline in the volume of the caudate nuclei (r = 0.60, p < 0.0001). The implications of these findings in age-associated motor abnormalities are discussed.

KW - Age-related changes

KW - Magnetic resonance image

KW - Putamen nuclei

KW - Stereology

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A magnetic resonance image study of age-related changes in human putamen nuclei

Abstract

Keywords

ASJC Scopus subject areas

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