TY - JOUR
T1 - A human cDNA encoding the 110-kDa a subunit of RNA polymerase II transcription factor elongin
AU - Aso, Teijiro
AU - Haque, Dewan
AU - Fukudome, Kenji
AU - Brower, Christopher S.
AU - Conaway, Joan Weliky
AU - Conaway, Ronald C.
N1 - Funding Information:
This work was supportedb y Grant GM41628 from the National Instituteso f Health and by funds from the H.A. and Mary K. Chapman Charitable Trust to the Oklahoma Medical ResearchF oundation.
PY - 1996/2/12
Y1 - 1996/2/12
N2 - A full-length cDNA encoding a human homolog of the approx. 110-kDa subunit (elongin A; El A) of the RNA polymerase II transcription factor, elongin, was isolated and sequenced. Comparison of the open reading frames of the human El A cDNA and the previously characterized rat El A cDNA [Aso et al., Science 269 (1995)1439-1443] indicates that they are 84% conserved in nucleotide sequence and encode 84% identical proteins.
AB - A full-length cDNA encoding a human homolog of the approx. 110-kDa subunit (elongin A; El A) of the RNA polymerase II transcription factor, elongin, was isolated and sequenced. Comparison of the open reading frames of the human El A cDNA and the previously characterized rat El A cDNA [Aso et al., Science 269 (1995)1439-1443] indicates that they are 84% conserved in nucleotide sequence and encode 84% identical proteins.
KW - Eukaryotic messenger RNA synthesis
KW - RNA chain elongation
KW - Transcriptional regulation
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U2 - 10.1016/0378-1119(95)00750-4
DO - 10.1016/0378-1119(95)00750-4
M3 - Article
C2 - 8654961
AN - SCOPUS:0030024496
SN - 0378-1119
VL - 168
SP - 277
EP - 278
JO - Gene
JF - Gene
IS - 2
ER -