TY - JOUR
T1 - A clinical measure of suicidal ideation, suicidal behavior, and associated symptoms in bipolar disorder
T2 - Psychometric properties of the Concise Health Risk Tracking Self-Report (CHRT-SR)
AU - Ostacher, Michael J.
AU - Nierenberg, Andrew A.
AU - Rabideau, Dustin
AU - Reilly-Harrington, Noreen A.
AU - Sylvia, Louisa G.
AU - Gold, Alexandra K.
AU - Shesler, Leah W.
AU - Ketter, Terence A.
AU - Bowden, Charles L.
AU - Calabrese, Joseph R.
AU - Friedman, Edward S.
AU - Iosifescu, Dan V.
AU - Thase, Michael E.
AU - Leon, Andrew C.
AU - Trivedi, Madhukar H.
N1 - Funding Information:
Dr. Iosifescu has had research funding from Aspect Medical, Forest and Ortho-McNeil and has received speaker honoraria from Reed Medical (sponsor of the MGH Psych Academy).
Funding Information:
The study was funded by NIH NO1MH80001. ClinicalTrials.gov number NCT00667745.
Funding Information:
The study was funded by National Institute of Mental Health , Contract NO1MH80001 . ClinicalTrials.gov number NCT00667745 .
Funding Information:
Dr. Friedman receives grant support from Novartis, St. Jude Medical, Medtronics, Repligen, Astra-Zeneca, Roche, and Takeda. He receives royalties from Springer.
Publisher Copyright:
© 2015 .
PY - 2015/12
Y1 - 2015/12
N2 - Objective: People with bipolar disorder are at high risk of suicide, but no clinically useful scale has been validated in this population. The aim of this study was to evaluate the psychometric properties in bipolar disorder of the 7- and 12-item versions of the Concise Health Risk Tracking Self-Report (CHRT-SR), a scale measuring suicidal ideation, suicidal behavior, and associated symptoms. Methods: The CHRT was administered to 283 symptomatic outpatients with bipolar I or II disorder who were randomized to receive lithium plus optimized personalized treatment (OPT), or OPT without lithium in a six month longitudinal comparative effectiveness trial. Participants were assessed using structured diagnostic interviews, clinician-rated assessments, and self-report questionnaires. Results: The internal consistency (Cronbach α) was 0.80 for the 7-item CHRT-SR and 0.90 for the 12-item CHRT-SR with a consistent factor structure, and three independent factors (current suicidal thoughts and plans, hopelessness, and perceived lack of social support) for the 7-item version. CHRT-SR scores are correlated with measures of depression, functioning, and quality of life, but not with mania scores. Conclusions: The 7- and 12-item CHRT-SR both had excellent psychometric properties in a sample of symptomatic subjects with bipolar disorder. The scale is highly correlated with depression, functioning, and quality of life, but not with mania. Future research is needed to determine whether the CHRT-SR will be able to predict suicide attempts in clinical practice.
AB - Objective: People with bipolar disorder are at high risk of suicide, but no clinically useful scale has been validated in this population. The aim of this study was to evaluate the psychometric properties in bipolar disorder of the 7- and 12-item versions of the Concise Health Risk Tracking Self-Report (CHRT-SR), a scale measuring suicidal ideation, suicidal behavior, and associated symptoms. Methods: The CHRT was administered to 283 symptomatic outpatients with bipolar I or II disorder who were randomized to receive lithium plus optimized personalized treatment (OPT), or OPT without lithium in a six month longitudinal comparative effectiveness trial. Participants were assessed using structured diagnostic interviews, clinician-rated assessments, and self-report questionnaires. Results: The internal consistency (Cronbach α) was 0.80 for the 7-item CHRT-SR and 0.90 for the 12-item CHRT-SR with a consistent factor structure, and three independent factors (current suicidal thoughts and plans, hopelessness, and perceived lack of social support) for the 7-item version. CHRT-SR scores are correlated with measures of depression, functioning, and quality of life, but not with mania scores. Conclusions: The 7- and 12-item CHRT-SR both had excellent psychometric properties in a sample of symptomatic subjects with bipolar disorder. The scale is highly correlated with depression, functioning, and quality of life, but not with mania. Future research is needed to determine whether the CHRT-SR will be able to predict suicide attempts in clinical practice.
KW - Bipolar disorder
KW - Evidence-based care
KW - Mood disorders
KW - Psychometrics
KW - Suicide
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U2 - 10.1016/j.jpsychires.2015.10.004
DO - 10.1016/j.jpsychires.2015.10.004
M3 - Article
C2 - 26476489
AN - SCOPUS:84945912275
SN - 0022-3956
VL - 71
SP - 126
EP - 133
JO - Journal of Psychiatric Research
JF - Journal of Psychiatric Research
ER -