A case of Susac syndrome with cervical spinal cord involvement on MRI

Le H. Hua; Stacy L. Donlon; Darin T. Okuda

doi:10.1016/j.jns.2013.11.040

A case of Susac syndrome with cervical spinal cord involvement on MRI

Le H. Hua, Stacy L. Donlon, Darin T. Okuda

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

We describe a typical case presentation of Susac syndrome with a novel MRI finding of cervical spinal cord involvement. A 25-year-old, 14-week gestation white woman presented with two episodes of encephalopathy, responsive to steroids, with abnormal brain magnetic resonance imaging (MRI) concerning for Susac syndrome. Further studies confirmed the clinical triad of encephalopathy, branch retinal artery occlusions and hearing loss pathognomonic for Susac syndrome. Cervical spine MRI demonstrated two focal areas of high-signal abnormality at C2 and C3. We provide a brief review of Susac syndrome, data regarding pregnancy in this rare syndrome, and discuss how this unique observation may assist in the medical management of such cases and contribute to the understanding of the underlying pathophysiology.

Original language	English (US)
Pages (from-to)	228-231
Number of pages	4
Journal	Journal of the Neurological Sciences
Volume	337
Issue number	1-2
DOIs	https://doi.org/10.1016/j.jns.2013.11.040
State	Published - Feb 15 2014

Keywords

Autoimmune disorder
Encephalopathy
Endotheliopathy
Microangiopathy
Spinal cord MRI
Susac syndrome

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1016/j.jns.2013.11.040

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abstract = "We describe a typical case presentation of Susac syndrome with a novel MRI finding of cervical spinal cord involvement. A 25-year-old, 14-week gestation white woman presented with two episodes of encephalopathy, responsive to steroids, with abnormal brain magnetic resonance imaging (MRI) concerning for Susac syndrome. Further studies confirmed the clinical triad of encephalopathy, branch retinal artery occlusions and hearing loss pathognomonic for Susac syndrome. Cervical spine MRI demonstrated two focal areas of high-signal abnormality at C2 and C3. We provide a brief review of Susac syndrome, data regarding pregnancy in this rare syndrome, and discuss how this unique observation may assist in the medical management of such cases and contribute to the understanding of the underlying pathophysiology.",

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AU - Donlon, Stacy L.

AU - Okuda, Darin T.

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A case of Susac syndrome with cervical spinal cord involvement on MRI

Abstract

Keywords

ASJC Scopus subject areas

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