[3 + 2]-Cycloadditions of Azomethine Imines and Ynolates

Sarah E. Winterton, Joseph M. Ready

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


A novel [3 + 2]-cycloaddition between azomethine imines and lithium ynolates is described to synthesize bicyclic pyrazolidinones. These bicyclic pyrazolidinones are versatile intermediates to form β-amino acids and monocyclic pyrazolidinones. High diastereoselectivity and stereospecificity allow access to optically active products.

Original languageEnglish (US)
Pages (from-to)2608-2611
Number of pages4
JournalOrganic Letters
Issue number11
StatePublished - Jun 3 2016

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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