2-Cyanopyridazin-3(2H)-ones: Effective and chemoselective electrophilic cyanating agents

Jeum Jong Kim, Deok Heon Kweon, Su Dong Cho, Ho Kyun Kim, Eun Young Jung, Sang Gyeong Lee, J R Falck, Yong Jin Yoon

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


2-Cyanopyridazin-3(2H)-ones are novel, effective, selective and electrophilic cyanating agents. A variety of amino, thiol and carbon nucleophiles are chemoselectively N-, S- or C-cyanated in excellent yield using 2-cyanopyridanzin-3(2H)-ones in water or tetrahydrofuran.

Original languageEnglish (US)
Pages (from-to)5889-5894
Number of pages6
Issue number24
StatePublished - Jun 13 2005


  • 2-Cyanopyridazin-3(2H)- ones
  • Electrophilic cyanating agent
  • N-, S- or C-cyanation

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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