Pharmacology - Sternweis Lab

Research output

Research output per year 1974 1981 1990 1991 1992 1993 1994 1995 1997 2001 2004 2018

• 99 Article
• 8 Review article
• 3 Chapter
• 1 Letter

Research output per year

Research output per year

Search results

• Article

  [13] Synthesis and applications of affinity matrix containing immobilized βγ subunits of G proteins

  Pang, I. H., Smrcka, A. V. & Sternweis, P. C., 1994, In: Methods in Enzymology. 237, p. 154-174 21 p.

  Research output: Contribution to journal › Article › peer-review

• A₁ adenosine receptors of bovine brain couple to guanine nucleotide-binding proteins G_i1, G_i2, and G_o

  Munshi, R., Pang, I. H., Sternweis, P. C. & Linden, J., 1991, In: Journal of Biological Chemistry. 266, 33, p. 22285-22289 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Adenosine A1 Receptors 100%
  • Guanine Nucleotides 92%
  • GTP-Binding Proteins 74%
  • Guanine 72%
  • Adenosine 71%
  129 Scopus citations

• Activated RhoA binds to the Pleckstrin Homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation

  Chen, Z., Medina, F., Liu, M. Y., Thomas, C., Sprang, S. R. & Sternweis, P. C., Jul 2 2010, In: Journal of Biological Chemistry. 285, 27, p. 21070-21081 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Rho Guanine Nucleotide Exchange Factors 100%
  • Pleckstrin Homology Domains 89%
  • GDP 82%
  • Guanosine 71%
  • platelet protein P47 65%
  48 Scopus citations

• Activated RhoA is a positive feedback regulator of the Lbc family of Rho guanine nucleotide exchange factor proteins

  Medina, F., Carter, A. M., Dada, O., Gutowski, S., Hadas, J., Chen, Z. & Sternweis, P. C., Apr 19 2013, In: Journal of Biological Chemistry. 288, 16, p. 11325-11333 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Rho Guanine Nucleotide Exchange Factors 100%
  • Pleckstrin Homology Domains 89%
  • GTP Phosphohydrolases 74%
  • Guanine 63%
  • Nucleotide 53%
  37 Scopus citations

• Activation of p115-RhoGEF requires direct association of Gα₁₃and the Dbl homology domain

  Chen, Z., Guo, L., Hadas, J., Gutowski, S., Sprang, S. R. & Sternweis, P. C., Jul 20 2012, In: Journal of Biological Chemistry. 287, 30, p. 25490-25500 11 p.

  Research output: Contribution to journal › Article › peer-review

  • G12 100%
  • Rho Guanine Nucleotide Exchange Factors 92%
  • Guanine 58%
  • Mutation 50%
  • Nucleotide 49%
  33 Scopus citations

• ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity

  Brown, H. A., Gutowski, S., Moomaw, C. R., Slaughter, C. & Sternwels, P. C., Dec 17 1993, In: Cell. 75, 6, p. 1137-1144 8 p.

  Research output: Contribution to journal › Article › peer-review

  • ADP-Ribosylation Factors 100%
  • Phospholipase D 87%
  • GTP-Binding Proteins 65%
  • Phosphatidic Acid 41%
  • Choline 35%
  862 Scopus citations

• A global analysis of cross-talk in a mammalian cellular signalling network

  Natarajan, M., Lin, K. M., Hsueh, R. C., Sternweis, P. C. & Ranganathan, R., Jun 2006, In: Nature cell biology. 8, 6, p. 571-580 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Electronic Data Processing 100%
  • Ligands 69%
  • Macrophages 68%
  • Phosphorylation 67%
  • Cytokines 61%
  198 Scopus citations

• Aluminum: A requirement for activation of the regulatory component of adenylate cyclase by fluoride

  Sternweis, P. C. & Gilman, A. G., 1982, In: Proceedings of the National Academy of Sciences of the United States of America. 79, 16 I, p. 4888-4891 4 p.

  Research output: Contribution to journal › Article › peer-review
  530 Scopus citations

• Analysis of the major patterns of B cell gene expression changes in response to short-term stimulation with 33 single ligands

  Zhu, X., Hart, R., Chang, M. S., Kim, J. W., Lee, S. Y., Cao, Y. A., Mock, D., Ke, E., Saunders, B., Alexander, A., Grossoehme, J., Lin, K. M., Yan, Z., Hsueh, R., Lee, J., Scheuermann, R. H., Fruman, D. A., Seaman, W., Subramaniam, S., Sternweis, P., & 2 othersSimon, M. I. & Choi, S., Dec 15 2004, In: Journal of Immunology. 173, 12, p. 7141-7149 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • B-Lymphocytes 100%
  • CD40 Ligand 96%
  • Ligands 91%
  • Gene Expression 77%
  • Interleukin-4 72%
  43 Scopus citations

• A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits

  Stephens, L., Smrcka, A., Cooke, F. T., Jackson, T. R., Sternweis, P. C. & Hawkins, P. T., Apr 8 1994, In: Cell. 77, 1, p. 83-93 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Phosphoinositide 100%
  • Protein Subunits 83%
  • Myeloid Cells 74%
  • Phosphatidylinositol 3-Kinase 74%
  • GTP-Binding Proteins 73%
  554 Scopus citations

• Antibodies to the α_q subfamily of guanine nucleotide-binding regulatory protein α subunits attenuate activation of phosphatidylinositol 4,5-bisphosphate hydrolysis by hormones

  Gutowski, S., Smrcka, A., Nowak, L., Wu, D., Simon, M. & Sternweis, P. C., 1991, In: Journal of Biological Chemistry. 266, 30, p. 20519-20524 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Phosphatidylinositol 100%
  • Protein Subunits 94%
  • Phosphatidylinositols 88%
  • Hormone 82%
  • GTP-Binding Proteins 82%
  299 Scopus citations

• Assays and characterization of mammalian phosphatidylinositol 4,5-bisphosphate-sensitive phospholipase D

  Jiang, X., Gutowski, S., Singer, W. D. & Sternweis, P. C., 2001, In: Methods in Enzymology. 345, p. 328-334 7 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Bradykinin modulates potassium and calcium currents in neuroblastoma hybrid cells via different pertussis toxin-insensitive pathways

  Wilk-Blaszczak, M. A., Gutowski, S., Sternweis, P. C. & Belardetti, F., Jan 1994, In: Neuron. 12, 1, p. 109-116 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Hybrid Cells 100%
  • Pertussis Toxin 93%
  • Bradykinin 92%
  • Neuroblastoma 82%
  • Potassium 74%
  40 Scopus citations

• Characterization of the Inhibitory (ε) Subunit of the Proton-Translocating Adenosine Triphosphatase from Escherichia Coli

  Sternweis, P. C., 1980, In: Biochemistry. 19, 3, p. 526-531 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Protons 100%
  • Adenosine Triphosphatases 98%
  • Adenosine 93%
  • Escherichia coli 68%
  • Strain 25%
  115 Scopus citations

• Characterization of the Purified Membrane Attachment (δ) Subunit of the Proton Translocating Adenosine Triphosphatase from Escherichia coli

  Sternweis, P. C. & Smith, J. B., Sep 1 1977, In: Biochemistry. 16, 18, p. 4020-4025 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Protons 100%
  • Adenosine Triphosphatases 98%
  • Adenosine 93%
  • Escherichia coli 68%
  • Proton 63%
  75 Scopus citations

• Chromatographic resolution and immunologic identification of the α₄₀ and α₄₁ subunits of guanine nucleotide-binding regulatory proteins from bovine brain

  Mumby, S., Pang, I. H., Gilman, A. G. & Sternweis, P. C., 1988, In: Journal of Biological Chemistry. 263, 4, p. 2020-2026 7 p.

  Research output: Contribution to journal › Article › peer-review

  • GTP-Binding Proteins 100%
  • Guanine 97%
  • Immune Sera 90%
  • Carrier Proteins 85%
  • Cattle 80%
  128 Scopus citations

• Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997)

  Taylor, P., Ross, E. M., Sternweis, P. C., Neubig, R. R. & McCammon, J. A., Jan 1 1997, In: Molecular Pharmacology. 52, 1, p. 1-5 5 p.

  Research output: Contribution to journal › Article › peer-review

• Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase

  Chen, Z., Gutowski, S. & Sternweis, P. C., Apr 2018, In: Data in Brief. 17, p. 356-362 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rho Guanine Nucleotide Exchange Factors 100%
  • Pleckstrin Homology Domains 89%
  • GTP Phosphohydrolases 74%
  • rho GTP-Binding Proteins 65%
  • Manuscripts 15%
  5 Scopus citations

• Deciphering signaling outcomes from a system of complex networks

  Hsueh, R. C., Natarajan, M., Fraser, I., Pond, B., Liu, J., Mumby, S., Han, H., Jiang, L. I., Simon, M. I., Taussig, R. & Sternweis, P. C., May 19 2009, In: Science signaling. 2, 71, p. ra22

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ligands 100%
  • Cytokines 87%
  • Toll-Like Receptor 4 81%
  • Signal Transduction 76%
  • Cyclic AMP 69%
  32 Scopus citations

• Differential G protein-mediated coupling of neurotransmitter receptors to Ca²⁺ channels in rat dorsal root ganglion neurons in vitro

  Ewald, D. A., Iok-Hou, P., Sternweis, P. C. & Miller, R. J., Feb 1989, In: Neuron. 2, 2, p. 1185-1193 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurotransmitter Receptor 100%
  • Bradykinin 91%
  • Spinal Ganglia 88%
  • GTP-Binding Proteins 81%
  • Neuropeptide Y 75%
  153 Scopus citations

• Direct regulation of p190RhoGEF by activated Rho and Rac GTPases

  Dada, O., Gutowski, S., Brautigam, C. A., Chen, Z. & Sternweis, P. C., Apr 2018, In: Journal of Structural Biology. 202, 1, p. 13-24 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rho Guanine Nucleotide Exchange Factors 100%
  • rho GTP-Binding Proteins 81%
  • GTP Phosphohydrolases 74%
  • Pleckstrin Homology Domains 66%
  • Cell Shape 19%
  11 Scopus citations

• Distinct roles of adenylyl cyclase VII in regulating the immune responses in mice

  Duan, B., Davis, R., Sadat, E. L., Collins, J., Sternweis, P. C., Yuan, D. & Jiang, L. I., Jul 1 2010, In: Journal of Immunology. 185, 1, p. 335-344 10 p.

  Research output: Contribution to journal › Article › peer-review

  • adenylyl cyclase 7 100%
  • Protein Isoforms 32%
  • T-Lymphocytes 31%
  • Immune System 24%
  • Second Messenger Systems 22%
  66 Scopus citations

• Effects of Mg²⁺ and the βγ-subunit complex on the interactions of guanine nucleotides with G proteins

  Higashijima, T., Ferguson, K. M. & Sternweis, P. C., 1987, In: Journal of Biological Chemistry. 262, 2, p. 762-766 5 p.

  Research output: Contribution to journal › Article › peer-review

  • GDP 100%
  • Guanine Nucleotides 97%
  • GTP-Binding Proteins 78%
  • Guanine 76%
  • Carrier Proteins 66%
  315 Scopus citations

• Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles

  Ktistakis, N. T., Brown, H. A., Waters, M. G., Sternweis, P. C. & Roth, M. G., Jul 1996, In: Journal of Cell Biology. 134, 2, p. 295-306 12 p.

  Research output: Contribution to journal › Article › peer-review

  • ADP-Ribosylation Factors 100%
  • Coated Vesicles 95%
  • Phospholipase D 87%
  • COP-Coated Vesicles 78%
  • Phosphatidic Acids 57%
  331 Scopus citations

• Functional characterization of p115 RhoGEF

  Wells, C., Jiang, X., Gutowski, S. & Sternweis, P. C., 2001, In: Methods in Enzymology. 345, p. 371-382 12 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• G protein γ subunits contain a 20-carbon isoprenoid

  Mumby, S. M., Casey, P. J., Gilman, A. G., Gutowski, S. & Sternweis, P. C., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 15, p. 5873-5877 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Carbon-20 100%
  • Terpenes 72%
  • Protein Subunits 67%
  • GTP-Binding Proteins 58%
  • Carrier Proteins 50%
  261 Scopus citations

• Guanine nucleotide-binding protein G(o)-induced coupling of neuropeptide Y receptors to Ca²⁺ channels in sensory neurons

  Ewald, D. A., Sternweis, P. C. & Miller, R. J., 1988, In: Proceedings of the National Academy of Sciences of the United States of America. 85, 10, p. 3633-3637 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neuropeptide Y Receptors 100%
  • Guanine Nucleotides 82%
  • Neuropeptide Y 77%
  • Sensory Receptor Cells 71%
  • Carrier Proteins 56%
  212 Scopus citations

• Identification of Potential Mechanisms for Regulation of p115 RhoGEF through Analysis of Endogenous and Mutant Forms of the Exchange Factor

  Wells, C. D., Gutowski, S., Bollag, G. & Sternweis, P. C., Aug 3 2001, In: Journal of Biological Chemistry. 276, 31, p. 28897-28905 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Lysophosphatidic Acid 100%
  • Rho Guanine Nucleotide Exchange Factors 99%
  • Sphingosine 1-Phosphate 50%
  • Agonist 30%
  • Pleckstrin Homology Domains 25%
  66 Scopus citations

• Influence of γ subunit prenylation on association of guanine nucleotide-binding regulatory proteins with membranes

  Muntz, K. H., Sternweis, P. C., Gilman, A. G. & Mumby, S. M., 1992, In: Molecular biology of the cell. 3, 1, p. 49-61 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Prenylation 100%
  • GTP-Binding Proteins 71%
  • Carrier Proteins 60%
  • Membranes 42%
  • COS Cells 33%
  140 Scopus citations

• Isolation of the α subunits of GTP-binding regulatory proteins by affinity chromatography with immobilized βγ subunits

  Pang, I. H. & Sternweis, P. C., 1989, In: Proceedings of the National Academy of Sciences of the United States of America. 86, 20, p. 7814-7818 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Affinity Chromatography 100%
  • GTP-Binding Proteins 93%
  • Sepharose 49%
  • Cattle 37%
  • tetrafluoroaluminate 26%
  71 Scopus citations

• Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain

  Sternweis, P. C. & Robishaw, J. D., 1984, In: Journal of Biological Chemistry. 259, 22, p. 13806-13813 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Guanine Nucleotides 100%
  • Transducin 79%
  • Guanine 78%
  • Nucleotide 66%
  • Cattle 64%
  999 Scopus citations

• Lipid modifications of G protein subunits: Myristoylation of G_oα increases its affinity for βγ

  Linder, M. E., Pang, I. H., Duronio, R. J., Gordon, J. I., Sternweis, P. C. & Gilman, A. G., Mar 5 1991, In: Journal of Biological Chemistry. 266, 7, p. 4654-4659 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Myristoylation 100%
  • Gi-Go GTP-Binding Protein alpha Subunits 91%
  • Recombinant Proteins 43%
  • Lipid 41%
  • Lipids 39%
  247 Scopus citations

• Mapping the Gα₁₃ binding interface of the rgRGS domain of p115RhoGEF

  Chen, Z., Singer, W. D., Wells, C. D., Sprang, S. R. & Sternweis, P. C., Mar 14 2003, In: Journal of Biological Chemistry. 278, 11, p. 9912-9919 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Rho Guanine Nucleotide Exchange Factors 100%
  • Protein Domains 65%
  • GTP-Binding Proteins 64%
  • GTPase-Activating Proteins 43%
  • Protein 26%
  37 Scopus citations

• Mechanisms for reversible regulation between G₁₃ and Rho exchange factors

  Wells, C. D., Liu, M. Y., Jackson, M., Gutowski, S., Sternweis, P. M., Rothstein, J. D., Kozasa, T. & Sternweis, P. C., Jan 11 2002, In: Journal of Biological Chemistry. 277, 2, p. 1174-1181 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Rho Factor 100%
  • GTP-Binding Protein Regulators 86%
  • Rho Guanine Nucleotide Exchange Factors 76%
  • GTPase-Activating Proteins 44%
  • Protein 23%
  92 Scopus citations

• Mechanisms of G protein action: Insight from reconstitution

  Sternweis, P. C. & Pang, I. H., 1990, In: Journal of General Physiology. 43 rd ANN. SYMP., p. 197-205 9 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Mechanisms of muscarinic receptor action on G(o) in reconstituted phospholipid vesicles

  Florio, V. A. & Sternweis, P. C., 1989, In: Journal of Biological Chemistry. 264, 7, p. 3909-3915 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Parasympathomimetic Agent 100%
  • Muscarinic Receptors 87%
  • Guanosine Triphosphate 84%
  • Agonist 76%
  • Phospholipids 71%
  186 Scopus citations

• Modeling species-specific diacylglycerol dynamics in the RAW 264.7 macrophage

  Callender, H. L., Horn, M. A., DeCamp, D. L., Sternweis, P. C. & Alex Brown, H., Feb 2010, In: Journal of Theoretical Biology. 262, 4, p. 679-690 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Macrophages 100%
  • Macrophage 92%
  • Diglycerides 71%
  • diacylglycerols 64%
  • macrophages 53%
  3 Scopus citations

• Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF

  Chen, Z., Guo, L., Sprang, S. R. & Sternweis, P. C., Jan 2011, In: Protein Science. 20, 1, p. 107-117 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rho Guanine Nucleotide Exchange Factors 100%
  • Guanine Nucleotides 80%
  • Guanine 63%
  • Nucleotide 53%
  • G12 36%
  30 Scopus citations

• p115 Rho GTPase activating protein interacts with MEKK1

  Christerson, L. B., Gallagher, E., Vanderbilt, C. A., Whitehurst, A. W., Wells, C., Kazempour, R., Sternweis, P. C. & Cobb, M. H., 2002, In: Journal of cellular physiology. 192, 2, p. 200-208 9 p.

  Research output: Contribution to journal › Article › peer-review

  • MAP Kinase Kinase Kinase 1 100%
  • rho GTPase-activating protein 98%
  • Protein 24%
  • Transcription Factor AP-1 18%
  • Cell Movement 8%
  26 Scopus citations

• Partial purification and characterization of Arf-sensitive phospholipase D from porcine brain

  Brown, H. A., Gutowski, S., Kahn, R. A. & Sternweis, P. C., Jun 23 1995, In: Journal of Biological Chemistry. 270, 25, p. 14935-14943 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Phospholipase D 100%
  • Swine 59%
  • Purification 50%
  • Chromatography 38%
  • Brain 36%
  134 Scopus citations

• Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects

  Xie, Z., Fang, M., Rivas, M. P., Faulkner, A. J., Sternweis, P. C., Engebrecht, J. & Bankaitis, V. A., Oct 13 1998, In: Proceedings of the National Academy of Sciences of the United States of America. 95, 21, p. 12346-12351 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phospholipid Transfer Proteins 100%
  • Phospholipase D 89%
  • Fungal Proteins 83%
  • Yeasts 36%
  • Phosphatidic Acids 14%
  147 Scopus citations

• Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A

  Ktistakis, N. T., Brown, H. A., Sternweis, P. C. & Roth, M. G., May 23 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 11, p. 4952-4956 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ADP-Ribosylation Factors 100%
  • Brefeldin A 90%
  • Phospholipase D 87%
  • Membranes 38%
  • Guanosine Triphosphate 34%
  183 Scopus citations

• Photoaffinity labeling of two rat liver plasma membrane proteins with [³²P]γ-azidoanilido GTP in response to vasopressin: Immunologic identification as α subunits of the G_q class of G proteins

  Wange, R. L., Smrcka, A. V., Sternweis, P. C. & Exton, J. H., 1991, In: Journal of Biological Chemistry. 266, 18, p. 11409-11412 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Gq-G11 GTP-Binding Protein alpha Subunits 100%
  • Photoaffinity Labelling 82%
  • Guanosine Triphosphate 68%
  • Vasopressins 67%
  • Blood Proteins 57%
  100 Scopus citations

• Purification and characterization of recombinant G_16α from Sf9 cells: Activation of purified phospholipase C isozymes by G-protein α subunits

  Kozasa, T., Hepler, J. R., Smrcka, A. V., Simon, M. I., Rhee, S. G., Sternweis, P. C. & Gilman, A. G., Oct 1 1993, In: Proceedings of the National Academy of Sciences of the United States of America. 90, 19, p. 9176-9180 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sf9 Cells 100%
  • Protein Subunits 83%
  • Type C Phospholipases 81%
  • Isoenzymes 72%
  • GTP-Binding Proteins 72%
  77 Scopus citations

• Purification and characterization of the α subunit of G₁₃

  Singer, W. D., Miller, R. T. & Sternweis, P. C., 1994, In: Journal of Biological Chemistry. 269, 31, p. 19796-19802 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrolysis 100%
  • Guanosine Triphosphate 76%
  • Purification 73%
  • Immune Sera 65%
  • G12-G13 GTP-Binding Protein alpha Subunits 64%
  71 Scopus citations

• Purification and properties of reconstitutively active and inactive adenosinetriphosphatase from Escherichia coli

  Futai, M., Sternweis, P. C. & Heppel, L. A., 1974, In: Proceedings of the National Academy of Sciences of the United States of America. 71, 7, p. 2725-2729 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenosine Triphosphatases 100%
  • Escherichia coli 69%
  • Membranes 25%
  • Adenosine Triphosphate 22%
  • Escherichia coli K12 19%
  233 Scopus citations

• Purification and properties of the regulatory component (G/F) of adenylate cyclase.

  Sternweis, P. C., Northup, J. K., Hanski, E., Schleifer, L. S., Smigel, M. D. & Gilman, A. G., 1981, In: Advances in cyclic nucleotide research. 14, p. 23-36 14 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Purification and properties of the regulatory component of adenylate cyclase

  Gilman, A. G., Sternweis, P. C. & Northup, J. K., 1981, In: Biochemical Society Transactions. 9, 2, p. 58P

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Purification from Sf9 cells and characterization of recombinant G_qα and Q_11α: Activation of purified phospholipase C isozymes by G_α subunits

  Hepler, J. R., Kozasa, T., Smrcka, A. V., Simon, M. I., Rhee, S. G., Sternweis, P. C. & Gilman, A. G., Jul 5 1993, In: Journal of Biological Chemistry. 268, 19, p. 14367-14375 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Sf9 Cells 100%
  • Type C Phospholipases 81%
  • Isoenzymes 72%
  • Purification 49%
  • Complementary DNA 37%
  254 Scopus citations

• Purification of Membrane Attachment and Inhibitory Subunits of the Proton Translocating Adenosine Triphosphatase from Escherichia coli

  Smith, J. B. & Sternweis, P. C., Jan 1 1977, In: Biochemistry. 16, 2, p. 306-311 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Protons 100%
  • Adenosine Triphosphatases 98%
  • Adenosine 93%
  • Polypeptide 81%
  • Escherichia coli 68%
  140 Scopus citations