Office of the Associate Dean - Southwestern Medical School - Administration

Research output

Research output per year 1973 1974 1975 1981 1982 1987 1988 1991 2018 2022

• 64 Article
• 2 Review article
• 1 Comment/debate

Research output per year

Research output per year

Search results

• 2010

  A serum protein-based algorithm for the detection of Alzheimer disease

  O'Bryant, S. E., Xiao, G., Barber, R., Reisch, J., Doody, R., Fairchild, T., Adams, P., Waring, S. & Diaz-Arrastia, R., Sep 2010, In: Archives of neurology. 67, 9, p. 1077-1081 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein 100%
  • Biomarkers 99%
  • Alzheimer's Disease 95%
  • Blood Proteins 73%
  • Alzheimer Disease 64%
  204 Scopus citations
• 2011

  A blood-based algorithm for the detection of Alzheimer's disease

  O'Bryant, S. E., Xiao, G., Barber, R., Reisch, J., Hall, J., Cullum, C. M., Doody, R., Fairchild, T., Adams, P., Wilhelmsen, K. & Diaz-Arrastia, R., Sep 2011, In: Dementia and Geriatric Cognitive Disorders. 32, 1, p. 55-62 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Alzheimer Disease 100%
  • Blood Proteins 68%
  • Biomarkers 67%
  • Neuropsychological Tests 55%
  • Area Under Curve 41%
  82 Scopus citations
• 2012

  Lipids and adipokines as risk factors for Alzheimer's disease

  Warren, M. W., Hynan, L. S., Weiner, M. F., Doody, R., Rountree, S., Capriles, V., Ballantyne, C., Darby, E., Dawson, T., Hittle, A., Khaleeg, A., O'Bryant, S., Grammas, P., Williams, B., Wu, C. K., Zhang, Y., Schrimsher, G., Dentino, A., Momeni, P., Hill, L., & 16 othersFairchild, T., Knebl, J., Barber, R., Mains, D., Alvarez, L., Adams, P., Rosenberg, R., Reisch, J., Huebinger, R., Svetlik, D., Murray, J. S. M., Sears, T., Royall, D., Hazuda, H., Palmer, R. & Polk, M., 2012, In: Journal of Alzheimer's Disease. 29, 1, p. 151-157 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adipokines 100%
  • dementia 87%
  • Alzheimer Disease 67%
  • Lipids 57%
  • Adiponectin 47%
  73 Scopus citations
• 2014

  Total cholesterol and neuropsychiatric symptoms in Alzheimer's disease: The impact of total cholesterol level and gender

  Hall, J. R., Wiechmann, A. R., Johnson, L. A., Edwards, M., Barber, R. C., Cunningham, R., Singh, M., O'Bryant, S. E., Doody, R., Roundtree, S., Pavlik, V., Chan, W., Massman, P., Darby, E., Evans, T., Williams, B., Schrimsher, G., Dentino, A., Orozco, R., Fairchild, T., & 16 othersKnebl, J., Mains, D., Alvarez, L., Adams, P., Rosenberg, R., Weiner, M., Quiceno, M., Reisch, J., Huebinger, R., Xiao, G., Svetlik, D., Werry, A., Smith, J., Royall, D., Palmer, R. & Polk, M., Nov 7 2014, In: Dementia and Geriatric Cognitive Disorders. 38, p. 300-309 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Alzheimer Disease 100%
  • Cholesterol 94%
  • Hypercholesterolemia 51%
  • Psychotic Disorders 48%
  • Apathy 33%
  10 Scopus citations
• 2015

  Lipoprotein-associated phospholipase A2, homocysteine, and Alzheimer's disease

  Texas Alzheimer's Disease Research and Care Consortium, Dec 1 2015, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 4, p. 464-471 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 1-Alkyl-2-acetylglycerophosphocholine Esterase 100%
  • Homocysteine 70%
  • Alzheimer Disease 50%
  • 5'-palmitoyl cytarabine 15%
  • Cardiovascular Diseases 11%
  25 Scopus citations
• 2016

  A novel Alzheimer disease locus located near the gene encoding tau protein

  Genetic and Environmental Risk in Alzheimer's Disease (GERAD) Consortium & IGAP Consortium, Jan 1 2016, In: Molecular psychiatry. 21, 1, p. 108-117 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • tau Proteins 100%
  • Single Nucleotide Polymorphism 66%
  • Alzheimer Disease 61%
  • Genes 32%
  • Exons 28%
  180 Scopus citations

• Assessment of the genetic variance of late-onset Alzheimer's disease

  Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In: Neurobiology of Aging. 41, p. 200.e13-200.e20

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alzheimer Disease 100%
  • Single Nucleotide Polymorphism 61%
  • Netrin Receptors 30%
  • Multifactorial Inheritance 22%
  • Amyloid beta-Protein Precursor 21%
  60 Scopus citations
• 2017

  Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

  Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R., & 429 othersHoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Jr, W. T. L., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Tsolaki, M., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Goate, A. M., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Holmans, P. A., Pericak-Vance, M. A., Amouyel, P., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In: Nature genetics. 49, 9, p. 1373-1384 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene Frequency 100%
  • Innate Immunity 94%
  • Alzheimer Disease 79%
  • Microglia 34%
  • Odds Ratio 32%
  626 Scopus citations

• Transethnic genome-wide scan identifies novel Alzheimer's disease loci

  Alzheimer's Disease Genetics Consortium, Jul 1 2017, In: Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • dementia 100%
  • Alzheimer Disease 77%
  • Genome 67%
  • Single Nucleotide Polymorphism 50%
  • Genome-Wide Association Study 41%
  123 Scopus citations
• 2018

  Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

  ARUK Consortium, GERAD/PERADES, CHARGE, ADGC, EADI, International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, Jan 1 2018, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cholesterol Ester Transfer Proteins 100%
  • HDL Cholesterol 63%
  • Alzheimer Disease 55%
  • Genes 28%
  • Single Nucleotide Polymorphism 17%
  2 Scopus citations

• Sex-specific association of apolipoprotein e with cerebrospinal fluid levels of tau

  Alzheimer's Disease Genetics Consortium and the Alzheimer's Disease Neuroimaging Initiative, Aug 1 2018, In: JAMA neurology. 75, 8, p. 989-998 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoproteins 100%
  • Apolipoproteins E 89%
  • Cerebrospinal Fluid 73%
  • Neurofibrillary Tangles 37%
  • Sex Characteristics 35%
  197 Scopus citations

• Sex-specific genetic predictors of Alzheimer’s disease biomarkers

  Alzheimer’S Disease Neuroimaging Initiative (Adni) & The Alzheimer Disease Genetics Consortium (Adgc), Dec 1 2018, In: Acta Neuropathologica. 136, 6, p. 857-872 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alzheimer Disease 100%
  • Biomarkers 83%
  • Genome-Wide Association Study 67%
  • Amyloid 61%
  • Endophenotypes 57%
  70 Scopus citations
• 2019

  Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

  Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Sep 1 2019, In: Nature genetics. 51, 9, p. 1423-1424 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Immunity 100%
  • Alzheimer Disease 95%
  • Meta-Analysis 91%
  • Lipids 80%
  45 Scopus citations

• Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

  Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In: Nature genetics. 51, 3, p. 414-430 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Immunity 100%
  • Alzheimer Disease 95%
  • Meta-Analysis 91%
  • Lipids 80%
  • Serum Amyloid A Protein 35%
  1515 Scopus citations
• 2020

  Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

  The Alzheimer’s Disease Genetics Consortium, Dec 1 2020, In: Nature communications. 11, 1, 667.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoprotein 100%
  • Homozygote 89%
  • Alzheimer Disease 63%
  • Apolipoprotein E4 55%
  • genes 31%
  225 Scopus citations
• 2022

  Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

  Alzheimer's Disease Genetics Consortium, Dec 2022, In: Scientific reports. 12, 1, 6117.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alzheimer Disease 100%
  • Single Nucleotide Polymorphism 48%
  • Genome-Wide Association Study 29%
  • Meta-Analysis 21%
  • Alleles 20%
  10 Scopus citations

• New insights into the genetic etiology of Alzheimer’s disease and related dementias

  EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE, Apr 1 2022, In: Nature genetics. 54, 4, p. 412-436 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dementia 100%
  • Alzheimer Disease 92%
  • Proxy 17%
  • Genome-Wide Association Study 17%
  • Microglia 17%
  556 Scopus citations